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PKD2 polycystin 2, transient receptor potential cation channel [ Opisthocomus hoazin ]

Gene ID: 104327386, updated on 3-Aug-2024

Summary

Gene symbol
PKD2
Gene description
polycystin 2, transient receptor potential cation channel
Locus tag
N306_01170
Gene type
protein coding
RefSeq status
MODEL
Organism
Opisthocomus hoazin
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Opisthocomiformes; Opisthocomidae; Opisthocomus
Orthologs
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Genomic context

See PKD2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current ASM69207v1 (GCF_000692075.1) Unplaced Scaffold NW_009900611.1 (133500..167544)

NW_009900611.1Genomic Context describing neighboring genes Neighboring gene matrix extracellular phosphoglycoprotein Neighboring gene secreted phosphoprotein 1 Neighboring gene ATP binding cassette subfamily G member 2 (JR blood group)

Genomic regions, transcripts, and products

Genomic Sequence:
NW_009900611.1 Unplaced Scaffold Reference ASM69207v1

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables muscle alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in detection of mechanical stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
polycystin-2
Names
Polycystin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Opisthocomus hoazin Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69207v1

Genomic

  1. NW_009900611.1 Reference ASM69207v1

    Range
    133500..167544
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009932285.1XP_009930587.1  polycystin-2

    UniProtKB/TrEMBL
    A0A091VZN1
    Conserved Domains (2) summary
    pfam08016
    Location:118539
    PKD_channel; Polycystin cation channel
    cl08302
    Location:584630
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...