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CD14 CD14 molecule [ Cariama cristata (Red-legged seriema) ]

Gene ID: 104166717, updated on 3-Aug-2024

Summary

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Gene symbol
CD14
Gene description
CD14 molecule
Locus tag
N322_06469
Gene type
protein coding
RefSeq status
MODEL
Organism
Cariama cristata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Cariamiformes; Cariamidae; Cariama
Orthologs
human mouse all
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Genomic context

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See CD14 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
1
Annotation release Status Assembly Chr Location
100 current ASM69053v1 (GCF_000690535.1) Unplaced Scaffold NW_009633369.1 (40143..41498, complement)

NW_009633369.1Genomic Context describing neighboring genes Neighboring gene stimulator of interferon response cGAMP interactor 1 Neighboring gene solute carrier family 35 member A4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009633369.1 Unplaced Scaffold Reference ASM69053v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables lipopolysaccharide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipopolysaccharide-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of non-canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type I interferon production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type II interferon production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor 4 signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of lipopolysaccharide receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
monocyte differentiation antigen CD14
Names
Toll-like receptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cariama cristata Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69053v1

Genomic

  1. NW_009633369.1 Reference ASM69053v1

    Range
    40143..41498 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009706739.1 → XP_009705041.1  monocyte differentiation antigen CD14

    UniProtKB/TrEMBL
    A0A091M9T2
    Conserved Domains (5) summary
    cd00116
    Location:184 → 317
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:165 → 188
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:306 → 343
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:285 → 339
    LRR_8; Leucine rich repeat
    cl00217
    Location:40 → 104
    pyrophosphatase; Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers.
Nucleotide Protein
Heading Accession and Version

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