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CAPN3 calpain 3 [ Cuculus canorus (common cuckoo) ]

Gene ID: 104067323, updated on 3-Aug-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
Locus tag
N303_08207
See related
EnsemblRapid:ENSCCOG00010003387
Gene type
protein coding
RefSeq status
MODEL
Organism
Cuculus canorus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Otidimorphae; Cuculiformes; Cuculidae; Cuculus
Also known as
Calpain-3
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_02 current bCucCan1.pri (GCF_017976375.1) 5 NC_071405.1 (53770401..53803110)
100 previous assembly ASM70932v1 (GCF_000709325.1) Unplaced Scaffold NW_009258113.1 (6956512..6985740)

Chromosome 5 - NC_071405.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 87A Neighboring gene glucosidase alpha, neutral C Neighboring gene zinc finger protein 106 Neighboring gene synaptosome associated protein 23

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_017976375.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bCucCan1.pri

Genomic

  1. NC_071405.1 Reference bCucCan1.pri

    Range
    53770401..53803110
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009570052.2 → XP_009568347.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A091GP17
    Related
    ENSCCOP00010004889.1, ENSCCOT00010005952.1
    Conserved Domains (5) summary
    cd00051
    Location:687 → 741
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:70 → 409
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:423 → 573
    Calpain_III; Calpain large subunit, domain III
    pfam13499
    Location:718 → 774
    EF-hand_7; EF-hand domain pair
    pfam16648
    Location:577 → 643
    Calpain_u2; Unstructured region on Calpain-3

  2. XM_054067300.1 → XP_053923275.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A091GP17
    Related
    ENSCCOP00010004907.1, ENSCCOT00010005970.1

  3. XM_054067301.1 → XP_053923276.1  calpain-3 isoform X3

Nucleotide Protein
Heading Accession and Version

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