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COMT catechol-O-methyltransferase [ Cuculus canorus (common cuckoo) ]

Gene ID: 104054659, updated on 10-Oct-2024

Summary

Gene symbol
COMT
Gene description
catechol-O-methyltransferase
Locus tag
N303_02147
See related
EnsemblRapid:ENSCCOG00010015070
Gene type
protein coding
RefSeq status
MODEL
Organism
Cuculus canorus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Otidimorphae; Cuculiformes; Cuculidae; Cuculus
Orthologs
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Genomic context

See COMT in Genome Data Viewer
Location:
chromosome: 17
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_02 current bCucCan1.pri (GCF_017976375.1) 17 NC_071417.1 (624613..646695)
100 previous assembly ASM70932v1 (GCF_000709325.1) Unplaced Scaffold NW_009243909.1 (651457..668227)

Chromosome 17 - NC_071417.1Genomic Context describing neighboring genes Neighboring gene G protein subunit beta 1 like Neighboring gene thioredoxin reductase 2 Neighboring gene uncharacterized LOC128853926 Neighboring gene ARVCF delta catenin family member Neighboring gene transport and golgi organization 2 homolog

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables catechol O-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in catecholamine catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in developmental process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in dopamine metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in dendrite IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
catechol O-methyltransferase
Names
Catechol O-methyltransferase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_017976375.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bCucCan1.pri

Genomic

  1. NC_071417.1 Reference bCucCan1.pri

    Range
    624613..646695
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054082733.1XP_053938708.1  catechol O-methyltransferase isoform X1

  2. XM_054082731.1XP_053938706.1  catechol O-methyltransferase isoform X1

  3. XM_054082732.1XP_053938707.1  catechol O-methyltransferase isoform X1

    Related
    ENSCCOP00010021743.1, ENSCCOT00010026635.1
  4. XM_054082730.1XP_053938705.1  catechol O-methyltransferase isoform X1

  5. XM_054082734.1XP_053938709.1  catechol O-methyltransferase isoform X2

  6. XM_009555700.2XP_009553995.1  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A091GDV2
    Conserved Domains (1) summary
    cl17173
    Location:88232
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  7. XM_054082729.1XP_053938704.1  catechol O-methyltransferase isoform X1