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CAPN3 calpain 3 [ Phalacrocorax carbo (great cormorant) ]

Gene ID: 104043793, updated on 3-Aug-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
Locus tag
N336_05182
Gene type
protein coding
RefSeq status
MODEL
Organism
Phalacrocorax carbo
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Suliformes; Phalacrocoracidae; Phalacrocorax
Also known as
Calpain-3
Orthologs
human mouse all
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Genomic context

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See CAPN3 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_04 current bPhaCar2.1 (GCF_963921805.1) 10 NC_087522.1 (22607660..22645480, complement)
100 previous assembly ASM70892v1 (GCF_000708925.1) Unplaced Scaffold NW_009144545.1 (7017..38267)

Chromosome 10 - NC_087522.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 23 Neighboring gene zinc finger protein 106 Neighboring gene glucosidase alpha, neutral C Neighboring gene transmembrane protein 87A Neighboring gene VPS39 subunit of HOPS complex

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of calpain complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_963921805.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bPhaCar2.1

Genomic

  1. NC_087522.1 Reference bPhaCar2.1

    Range
    22607660..22645480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064462450.1 → XP_064318520.1  calpain-3 isoform X4

    UniProtKB/TrEMBL
    A0A093T705

  2. XM_064462448.1 → XP_064318518.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A093T705

  3. XM_064462449.1 → XP_064318519.1  calpain-3 isoform X3

    UniProtKB/TrEMBL
    A0A093T705

  4. XM_009503483.2 → XP_009501778.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A093T705
    Conserved Domains (5) summary
    cd00051
    Location:687 → 741
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:70 → 409
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:423 → 573
    Calpain_III; Calpain large subunit, domain III
    pfam13499
    Location:718 → 774
    EF-hand_7; EF-hand domain pair
    pfam16648
    Location:586 → 643
    Calpain_u2; Unstructured region on Calpain-3

  5. XM_064462451.1 → XP_064318521.1  calpain-3 isoform X5

  6. XM_064462452.1 → XP_064318522.1  calpain-3 isoform X6

Nucleotide Protein
Heading Accession and Version

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