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HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 103782784, updated on 18-Sep-2024

Summary

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Gene symbol
HOGA1
Gene description
4-hydroxy-2-oxoglutarate aldolase 1
See related
Ensembl:ENSPPAG00000025810
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See HOGA1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 8 NC_073257.2 (109496181..109524859)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 10 NC_073259.1 (109501500..109531789)

Chromosome 8 - NC_073257.2Genomic Context describing neighboring genes Neighboring gene ubiquitin domain containing 1 Neighboring gene ankyrin repeat domain 2 Neighboring gene chromosome 8 C10orf62 homolog Neighboring gene MORN repeat containing 4 Neighboring gene phosphatidylinositol 4-kinase type 2 alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables (R,S)-4-hydroxy-2-oxoglutarate aldolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glyoxylate catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
4-hydroxy-2-oxoglutarate aldolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073257.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    109496181..109524859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008950751.4 → XP_008948999.1  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_008948999.1

    UniProtKB/TrEMBL
    A0A2R8ZPI7
    Related
    ENSPPAP00000006856.1
    Conserved Domains (1) summary
    cd00408
    Location:38 → 321
    DHDPS-like; Dihydrodipicolinate synthase family

  2. XM_008950753.4 → XP_008949001.1  4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_008949001.1

    Conserved Domains (2) summary
    cd00408
    Location:70 → 158
    DHDPS-like; Dihydrodipicolinate synthase family
    cl21457
    Location:35 → 61
    TIM_phosphate_binding; TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate ...
Nucleotide Protein
Heading Accession and Version

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