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Fancm FA complementation group M [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103751929, updated on 11-Mar-2024

Summary

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Gene symbol
Fancm
Gene description
FA complementation group M
See related
Ensembl:ENSNGAG00000017199
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
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Genomic context

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See Fancm in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008357649.1 (543231..611148)

NW_008357649.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD127 Neighboring gene pre-mRNA processing factor 39 Neighboring gene FKBP prolyl isomerase 3 Neighboring gene MIS18 binding protein 1 Neighboring gene PRAME family member 3-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008357649 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via synthesis-dependent strand annealing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in interstrand cross-link repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in replication fork reversal IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
Fanconi anemia group M protein
Names
Fanconi anemia complementation group M

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008357649.1 Reference S.galili_v1.0 Primary Assembly

    Range
    543231..611148
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008855544.3 → XP_008853766.1  Fanconi anemia group M protein isoform X1

    UniProtKB/TrEMBL
    A0A8C6RFU9
    Related
    ENSNGAP00000016489.1, ENSNGAT00000022108.1
    Conserved Domains (4) summary
    COG1111
    Location:83 → 617
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    COG1948
    Location:1802 → 2020
    MUS81; ERCC4-type nuclease [Replication, recombination and repair]
    pfam09444
    Location:1491 → 1549
    MRC1; MRC1-like domain
    pfam16783
    Location:674 → 787
    FANCM-MHF_bd; FANCM to MHF binding domain

  2. XM_029557429.1 → XP_029413289.1  Fanconi anemia group M protein isoform X2

    UniProtKB/TrEMBL
    A0A8C6RFU9
    Conserved Domains (4) summary
    COG1111
    Location:83 → 588
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    COG1948
    Location:1773 → 1991
    MUS81; ERCC4-type nuclease [Replication, recombination and repair]
    pfam09444
    Location:1462 → 1520
    MRC1; MRC1-like domain
    pfam16783
    Location:645 → 758
    FANCM-MHF_bd; FANCM to MHF binding domain

  3. XM_029557430.1 → XP_029413290.1  Fanconi anemia group M protein isoform X3

    Conserved Domains (4) summary
    COG1948
    Location:1323 → 1541
    MUS81; ERCC4-type nuclease [Replication, recombination and repair]
    cd18801
    Location:1 → 110
    SF2_C_FANCM_Hef; C-terminal helicase domain of Fanconi anemia group M family helicases
    pfam09444
    Location:1012 → 1070
    MRC1; MRC1-like domain
    pfam16783
    Location:195 → 308
    FANCM-MHF_bd; FANCM to MHF binding domain
Nucleotide Protein
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