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Arhgap12 Rho GTPase activating protein 12 [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103748003, updated on 11-Mar-2024

Summary

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Gene symbol
Arhgap12
Gene description
Rho GTPase activating protein 12
See related
Ensembl:ENSNGAG00000017168
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
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Genomic context

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See Arhgap12 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008353342.1 (4517421..4660529, complement)

NW_008353342.1Genomic Context describing neighboring genes Neighboring gene pre-mRNA-splicing regulator WTAP-like Neighboring gene small nucleolar RNA SNORA73 family Neighboring gene mitochondrial import inner membrane translocase subunit Tim8 A pseudogene Neighboring gene low molecular weight phosphotyrosine protein phosphatase-like Neighboring gene kinesin family member 5B

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008353342 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. Malik A, et al. PLoS One, 2011. PMID 21857902, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008353342.1 Reference S.galili_v1.0 Primary Assembly

    Range
    4517421..4660529 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008850544.3 → XP_008848766.1  rho GTPase-activating protein 12 isoform X5

    Conserved Domains (5) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    cd04403
    Location:572 → 757
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:383 → 494
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00397
    Location:268 → 293
    WW; WW domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  2. XM_008850543.3 → XP_008848765.1  rho GTPase-activating protein 12 isoform X4

    UniProtKB/TrEMBL
    A0A8C6RGQ8
    Related
    ENSNGAP00000016436.1, ENSNGAT00000022054.1
    Conserved Domains (5) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 362
    PRP40; Splicing factor [RNA processing and modification]
    cd04403
    Location:574 → 759
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:385 → 496
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  3. XM_008850542.3 → XP_008848764.1  rho GTPase-activating protein 12 isoform X3

    Conserved Domains (5) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 362
    PRP40; Splicing factor [RNA processing and modification]
    cd04403
    Location:599 → 784
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:410 → 521
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  4. XM_008850540.3 → XP_008848762.1  rho GTPase-activating protein 12 isoform X2

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd04403
    Location:621 → 806
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00397
    Location:268 → 293
    WW; WW domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  5. XM_029554773.1 → XP_029410633.1  rho GTPase-activating protein 12 isoform X1

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd04403
    Location:646 → 831
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00397
    Location:268 → 293
    WW; WW domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  6. XM_008850539.3 → XP_008848761.1  rho GTPase-activating protein 12 isoform X1

    See identical proteins and their annotated locations for XP_008848761.1

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd04403
    Location:646 → 831
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00397
    Location:268 → 293
    WW; WW domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  7. XM_029554774.1 → XP_029410634.1  rho GTPase-activating protein 12 isoform X1

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd04403
    Location:646 → 831
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00397
    Location:268 → 293
    WW; WW domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
Nucleotide Protein
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