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Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103738666, updated on 11-Mar-2024

Summary

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Gene symbol
Apex2
Gene description
apurinic/apyrimidinic endodeoxyribonuclease 2
See related
Ensembl:ENSNGAG00000013576
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
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Genomic context

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See Apex2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
6
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008342711.1 (701625..710233)

NW_008342711.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA11 Neighboring gene trophinin Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Neighboring gene small nucleolar RNA SNORA62/SNORA6 family Neighboring gene 5'-aminolevulinate synthase 2 Neighboring gene allograft inflammatory factor 1-like pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008342711 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. Malik A, et al. PLoS One, 2011. PMID 21857902, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded DNA 3'-5' DNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoric diester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA-(apurinic or apyrimidinic site) lyase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008342711.1 Reference S.galili_v1.0 Primary Assembly

    Range
    701625..710233
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008838765.3 → XP_008836987.1  DNA-(apurinic or apyrimidinic site) lyase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C6R0C1
    Related
    ENSNGAP00000011420.1, ENSNGAT00000016967.1
    Conserved Domains (2) summary
    cd09088
    Location:3 → 306
    Ape2-like_AP-endo; Human Ape2-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases
    pfam06839
    Location:461 → 508
    zf-GRF; GRF zinc finger

  2. XM_008838766.3 → XP_008836988.1  DNA-(apurinic or apyrimidinic site) lyase 2 isoform X2

    Conserved Domains (2) summary
    cd09088
    Location:29 → 284
    Ape2-like_AP-endo; Human Ape2-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases
    pfam06839
    Location:439 → 486
    zf-GRF; GRF zinc finger
Nucleotide Protein
Heading Accession and Version

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