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Dhx58 DExH-box helicase 58 [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103735886, updated on 11-Mar-2024

Summary

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Gene symbol
Dhx58
Gene description
DExH-box helicase 58
See related
Ensembl:ENSNGAG00000017107
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
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Genomic context

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See Dhx58 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008340203.1 (1799095..1810580, complement)

NW_008340203.1Genomic Context describing neighboring genes Neighboring gene NFKB inhibitor interacting Ras like 2 Neighboring gene zinc finger protein 385C Neighboring gene chromosome unknown C17orf113 homolog Neighboring gene lysine acetyltransferase 2A Neighboring gene heat shock protein family B (small) member 9

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008340203 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. Malik A, et al. PLoS One, 2011. PMID 21857902, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of interferon-beta production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
probable ATP-dependent RNA helicase DHX58

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008340203.1 Reference S.galili_v1.0 Primary Assembly

    Range
    1799095..1810580 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029564613.1 → XP_029420473.1  probable ATP-dependent RNA helicase DHX58

    UniProtKB/TrEMBL
    A0A8C6RCS3
    Related
    ENSNGAP00000016349.1, ENSNGAT00000021964.1
    Conserved Domains (4) summary
    cd12090
    Location:227 → 344
    MDA5_ID; Insert domain of MDA5
    cd18802
    Location:349 → 483
    SF2_C_dicer; C-terminal helicase domain of the endoribonuclease Dicer
    cl13152
    Location:552 → 664
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains
    cl28899
    Location:1 → 200
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

  2. XM_008835284.2 → XP_008833506.1  probable ATP-dependent RNA helicase DHX58

    UniProtKB/TrEMBL
    A0A8C6RCS3
    Conserved Domains (4) summary
    cd12090
    Location:227 → 344
    MDA5_ID; Insert domain of MDA5
    cd18802
    Location:349 → 483
    SF2_C_dicer; C-terminal helicase domain of the endoribonuclease Dicer
    cl13152
    Location:552 → 664
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains
    cl28899
    Location:1 → 200
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
Nucleotide Protein
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