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Asb3 ankyrin repeat and SOCS box containing 3 [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103725723, updated on 11-Mar-2024

Summary

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Gene symbol
Asb3
Gene description
ankyrin repeat and SOCS box containing 3
See related
Ensembl:ENSNGAG00000021703
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
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Genomic context

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See Asb3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008359442.1 (3562085..3710111)

NW_008359442.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene putative 60S ribosomal protein L37a Neighboring gene endoplasmic reticulum lectin 1 Neighboring gene 40S ribosomal protein S3a-like Neighboring gene ChaC glutathione specific gamma-glutamylcyclotransferase 2 Neighboring gene glycosaminoglycan xylosylkinase pseudogene Neighboring gene 60S acidic ribosomal protein P0 pseudogene Neighboring gene RNA 3'-terminal phosphate cyclase pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008359442 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. Malik A, et al. PLoS One, 2011. PMID 21857902, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ankyrin repeat and SOCS box protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008359442.1 Reference S.galili_v1.0 Primary Assembly

    Range
    3562085..3710111
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017795581.2 → XP_017651070.1  ankyrin repeat and SOCS box protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C6RU88, A0A8C6RXU2
    Related
    ENSNGAP00000023027.1, ENSNGAT00000028716.1
    Conserved Domains (4) summary
    cd03722
    Location:458 → 508
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:216 → 309
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:22 → 237
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_008823021.3 → XP_008821243.1  ankyrin repeat and SOCS box protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C6RU88, A0A8C6RXU2
    Conserved Domains (4) summary
    cd03722
    Location:458 → 508
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:216 → 309
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:22 → 237
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_029558623.1 → XP_029414483.1  ankyrin repeat and SOCS box protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C6RU88
    Conserved Domains (4) summary
    cd03722
    Location:477 → 527
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:165 → 195
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:235 → 328
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:41 → 256
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_029558624.1 → XP_029414484.1  ankyrin repeat and SOCS box protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C6RU88, A0A8C6RXU2
    Conserved Domains (4) summary
    cd03722
    Location:458 → 508
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:216 → 309
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:22 → 237
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
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