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CD44 CD44 molecule (IN blood group) [ Ursus maritimus (polar bear) ]

Gene ID: 103659318, updated on 11-Mar-2024

Summary

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Gene symbol
CD44
Gene description
CD44 molecule (IN blood group)
See related
Ensembl:ENSUMAG00000017982
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See CD44 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024424786.1 (20890472..20975795)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907078.1 (1915122..2000231, complement)

NW_024424786.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121104759 Neighboring gene uncharacterized LOC121104760 Neighboring gene uncharacterized LOC103659317 Neighboring gene solute carrier family 1 member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of macrophage migration inhibitory factor receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CD44 antigen
Names
CD44 molecule (Indian blood group)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024424786.1 Reference ASM1731132v1 Primary Assembly

    Range
    20890472..20975795
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008686804.2 → XP_008685026.1  CD44 antigen isoform X1

    UniProtKB/TrEMBL
    A0A384BR12, A0A452UUB2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  2. XM_008686805.2 → XP_008685027.1  CD44 antigen isoform X2

    UniProtKB/TrEMBL
    A0A384BR39, A0A452UUY1
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  3. XM_008686806.2 → XP_008685028.1  CD44 antigen isoform X3

    UniProtKB/TrEMBL
    A0A384BR09, A0A452UUB2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  4. XM_008686807.2 → XP_008685029.1  CD44 antigen isoform X4

    UniProtKB/TrEMBL
    A0A384BS07, A0A452UUY1
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  5. XM_008686808.2 → XP_008685030.1  CD44 antigen isoform X5

    UniProtKB/TrEMBL
    A0A384BS91, A0A452UUB2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  6. XM_008686809.2 → XP_008685031.1  CD44 antigen isoform X6

    UniProtKB/TrEMBL
    A0A384BR17, A0A452UUB2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  7. XM_008686810.2 → XP_008685032.1  CD44 antigen isoform X7

    UniProtKB/TrEMBL
    A0A384BR44, A0A452UUB2
    Related
    ENSUMAP00000024718.1
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  8. XM_008686811.2 → XP_008685033.1  CD44 antigen isoform X8

    UniProtKB/TrEMBL
    A0A384BR14, A0A452UUY1
    Related
    ENSUMAP00000024727.1

  9. XM_040638946.1 → XP_040494880.1  CD44 antigen isoform X9

    UniProtKB/TrEMBL
    A0A452UU99, A0A8M1GIV0
    Conserved Domains (2) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
    pfam09595
    Location:196 → 358
    Metaviral_G; Metaviral_G glycoprotein

  10. XM_008686812.2 → XP_008685034.1  CD44 antigen isoform X10

    UniProtKB/TrEMBL
    A0A384BS13, A0A452UV03
    Related
    ENSUMAP00000024743.1
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  11. XM_008686813.2 → XP_008685035.1  CD44 antigen isoform X11

    UniProtKB/TrEMBL
    A0A384BS94, A0A452UUB9
    Related
    ENSUMAP00000024756.1
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  12. XM_008686814.2 → XP_008685036.1  CD44 antigen isoform X12

    UniProtKB/TrEMBL
    A0A384BR22, A0A452UUB9
    Related
    ENSUMAP00000024761.1
    Conserved Domains (1) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
Nucleotide Protein
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