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DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease [ Ursus maritimus (polar bear) ]

Gene ID: 103659202, updated on 11-Mar-2024

Summary

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Gene symbol
DIS3
Gene description
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
See related
Ensembl:ENSUMAG00000009496
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See DIS3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024423344.1 (46396600..46425195, complement)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907072.1 (3375659..3402977, complement)

NW_024423344.1Genomic Context describing neighboring genes Neighboring gene mitotic spindle organizing protein 1 Neighboring gene BORA aurora kinase A activator Neighboring gene progesterone immunomodulatory binding factor 1 Neighboring gene KLF transcription factor 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in rRNA catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cytoplasmic exosome (RNase complex) IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of nuclear exosome (RNase complex) IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
exosome complex exonuclease RRP44

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024423344.1 Reference ASM1731132v1 Primary Assembly

    Range
    46396600..46425195 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008686673.2 → XP_008684895.2  exosome complex exonuclease RRP44 isoform X1

    UniProtKB/TrEMBL
    A0A384BRW2, A0A452TZE2
    Conserved Domains (2) summary
    COG0557
    Location:205 → 930
    VacB; Exoribonuclease R [Transcription]
    cd09862
    Location:9 → 197
    PIN_Rrp44-like; VapC-like PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs

  2. XM_040623468.1 → XP_040479402.1  exosome complex exonuclease RRP44 isoform X3

    UniProtKB/TrEMBL
    A0A452TZA8, A0A8M1FBZ1
    Conserved Domains (2) summary
    COG0557
    Location:175 → 900
    VacB; Exoribonuclease R [Transcription]
    cd09862
    Location:9 → 167
    PIN_Rrp44-like; VapC-like PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs

  3. XM_040623465.1 → XP_040479399.1  exosome complex exonuclease RRP44 isoform X2

    UniProtKB/TrEMBL
    A0A452TZE2, A0A8M1FFC0
    Conserved Domains (2) summary
    COG0557
    Location:43 → 768
    VacB; Exoribonuclease R [Transcription]
    cl28905
    Location:5 → 35
    PIN_SF; PIN (PilT N terminus) domain: Superfamily
Nucleotide Protein
Heading Accession and Version

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