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PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Galeopterus variegatus (Sunda flying lemur) ]

Gene ID: 103601422, updated on 11-Mar-2024

Summary

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Gene symbol
PFKFB1
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Galeopterus variegatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Dermoptera; Cynocephalidae; Galeopterus
Orthologs
human mouse all
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Genomic context

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See PFKFB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current G_variegatus-3.0.2 (GCF_000696425.1) Unplaced Scaffold NW_007729839.1 (110518..177809, complement)

NW_007729839.1Genomic Context describing neighboring genes Neighboring gene lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase-like Neighboring gene trophinin-like Neighboring gene trophinin-like Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene 5'-aminolevulinate synthase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007729839 unplaced scaffold reference G_variegatus-3.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Galeopterus variegatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference G_variegatus-3.0.2 Primary Assembly

Genomic

  1. NW_007729839.1 Reference G_variegatus-3.0.2 Primary Assembly

    Range
    110518..177809 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008585827.1 → XP_008584049.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X4

    Conserved Domains (2) summary
    pfam00300
    Location:189 → 372
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:6 → 186
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_008585825.1 → XP_008584047.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    Conserved Domains (3) summary
    pfam00300
    Location:257 → 440
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:33 → 254
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:47 → 200
    AAA_33; AAA domain

  3. XM_008585824.1 → XP_008584046.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    Conserved Domains (3) summary
    pfam00300
    Location:260 → 443
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:36 → 257
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:50 → 203
    AAA_33; AAA domain

  4. XM_008585826.1 → XP_008584048.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    Conserved Domains (3) summary
    pfam00300
    Location:232 → 415
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 229
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:44 → 175
    AAA_33; AAA domain
Nucleotide Protein
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