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LOC103587552 E3 ubiquitin-protein ligase CBL-like [ Galeopterus variegatus (Sunda flying lemur) ]

Gene ID: 103587552, updated on 22-Oct-2023

Summary

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Gene symbol
LOC103587552
Gene description
E3 ubiquitin-protein ligase CBL-like
Gene type
protein coding
RefSeq status
MODEL
Organism
Galeopterus variegatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Dermoptera; Cynocephalidae; Galeopterus
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Genomic context

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See LOC103587552 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
2
Annotation release Status Assembly Chr Location
100 current G_variegatus-3.0.2 (GCF_000696425.1) Unplaced Scaffold NW_007726571.1 (340419..343197, complement)

NW_007726571.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103587549 Neighboring gene uncharacterized LOC103587551 Neighboring gene heterogeneous nuclear ribonucleoprotein K Neighboring gene Q-nucleotide N-glycosylase 1 Neighboring gene kinesin family member 27 Neighboring gene G kinase anchoring protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007726571 unplaced scaffold reference G_variegatus-3.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Galeopterus variegatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference G_variegatus-3.0.2 Primary Assembly

Genomic

  1. NW_007726571.1 Reference G_variegatus-3.0.2 Primary Assembly

    Range
    340419..343197 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008569046.1 → XP_008567268.1  LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL-like

    Conserved Domains (5) summary
    cd09920
    Location:254 → 350
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd00162
    Location:379 → 421
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    cd14393
    Location:866 → 904
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    pfam02262
    Location:52 → 173
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:177 → 259
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
Nucleotide Protein
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