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arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 [ Cynoglossus semilaevis (tongue sole) ]

Gene ID: 103385913, updated on 11-Mar-2024

Summary

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Gene symbol
arhgef11
Gene description
Rho guanine nucleotide exchange factor (GEF) 11
See related
Ensembl:ENSCSEG00000000199
Gene type
protein coding
RefSeq status
MODEL
Organism
Cynoglossus semilaevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
Orthologs
human zebrafish all
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Genomic context

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See arhgef11 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
41
Annotation release Status Assembly Chr Location
102 current Cse_v1.0 (GCF_000523025.1) 1 NC_024307.1 (23127497..23148281)

Chromosome 1 - NC_024307.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103385895 Neighboring gene myeloid-associated differentiation marker homolog Neighboring gene uncharacterized LOC107988859 Neighboring gene uncharacterized LOC107988858 Neighboring gene uncharacterized LOC112487750 Neighboring gene vang-like protein 2 Neighboring gene uncharacterized LOC103385976

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024307.1 Chromosome 1 Reference Cse_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 11
Names
Rho guanine nucleotide exchange factor 11

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cynoglossus semilaevis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cse_v1.0 Primary Assembly

Genomic

  1. NC_024307.1 Reference Cse_v1.0 Primary Assembly

    Range
    23127497..23148281
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008319939.3 → XP_008318161.1  rho guanine nucleotide exchange factor 11 isoform X1

    UniProtKB/TrEMBL
    A0A3P8UAD6, A0A3P8UJ08
    Related
    ENSCSEP00000000253.1, ENSCSET00000000277.1
    Conserved Domains (4) summary
    cd00992
    Location:49 → 123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00621
    Location:751 → 932
    RhoGEF; RhoGEF domain
    cl02565
    Location:305 → 450
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:949 → 1083
    PH-like; Pleckstrin homology-like domain

  2. XM_025060234.1 → XP_024916002.1  rho guanine nucleotide exchange factor 11 isoform X3

    UniProtKB/TrEMBL
    A0A3P8UJ08
    Related
    ENSCSEP00000000265.1, ENSCSET00000000289.1
    Conserved Domains (4) summary
    cd00992
    Location:49 → 123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00621
    Location:751 → 931
    RhoGEF; RhoGEF domain
    cl02565
    Location:305 → 450
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:949 → 1083
    PH-like; Pleckstrin homology-like domain

  3. XM_025060240.1 → XP_024916008.1  rho guanine nucleotide exchange factor 11 isoform X6

    UniProtKB/TrEMBL
    A0A3P8UAE0, A0A3P8UJ08
    Related
    ENSCSEP00000000258.1, ENSCSET00000000282.1
    Conserved Domains (4) summary
    cd00992
    Location:49 → 123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00621
    Location:751 → 931
    RhoGEF; RhoGEF domain
    cl02565
    Location:305 → 450
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:949 → 1083
    PH-like; Pleckstrin homology-like domain

  4. XM_025060237.1 → XP_024916005.1  rho guanine nucleotide exchange factor 11 isoform X5

    UniProtKB/TrEMBL
    A0A3P8UCV9, A0A3P8UJ08
    Related
    ENSCSEP00000000257.1, ENSCSET00000000281.1
    Conserved Domains (4) summary
    cd00992
    Location:49 → 123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00621
    Location:735 → 915
    RhoGEF; RhoGEF domain
    cl02565
    Location:305 → 450
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:933 → 1067
    PH-like; Pleckstrin homology-like domain

  5. XM_017034159.2 → XP_016889648.1  rho guanine nucleotide exchange factor 11 isoform X2

    UniProtKB/TrEMBL
    A0A3P8UJ08

  6. XM_025060236.1 → XP_024916004.1  rho guanine nucleotide exchange factor 11 isoform X4

    UniProtKB/TrEMBL
    A0A3P8UJ12
    Related
    ENSCSEP00000000270.1, ENSCSET00000000294.1
    Conserved Domains (4) summary
    cd00992
    Location:49 → 123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00621
    Location:741 → 921
    RhoGEF; RhoGEF domain
    cl02565
    Location:305 → 450
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:939 → 1073
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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