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EDEM2 ER degradation enhancing alpha-mannosidase like protein 2 [ Eptesicus fuscus (big brown bat) ]

Gene ID: 103293348, updated on 30-Mar-2024

Summary

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Gene symbol
EDEM2
Gene description
ER degradation enhancing alpha-mannosidase like protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Eptesicus fuscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Eptesicus
Orthologs
human mouse all
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Genomic context

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See EDEM2 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_03 current DD_ASM_mEF_20220401 (GCF_027574615.1) 12 NC_072484.1 (35229284..35263129, complement)
101 previous assembly EptFus1.0 (GCF_000308155.1) Unplaced Scaffold NW_007370705.1 (8477744..8511042)

Chromosome 12 - NC_072484.1Genomic Context describing neighboring genes Neighboring gene myosin heavy chain 7B Neighboring gene microRNA mir-499 Neighboring gene transient receptor potential cation channel subfamily C member 4 associated protein Neighboring gene ubiquitin-like domain-containing CTD phosphatase 1 Neighboring gene polyadenylate-binding protein 4-like Neighboring gene protein C receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endoplasmic reticulum mannose trimming IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mannose trimming involved in glycoprotein ERAD pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ER degradation-enhancing alpha-mannosidase-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027574615.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference DD_ASM_mEF_20220401

Genomic

  1. NC_072484.1 Reference DD_ASM_mEF_20220401

    Range
    35229284..35263129 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054723947.1 → XP_054579922.1  ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X2

  2. XM_008149694.3 → XP_008147916.1  ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1

    Conserved Domains (1) summary
    pfam01532
    Location:42 → 480
    Glyco_hydro_47; Glycosyl hydrolase family 47
Nucleotide Protein
Heading Accession and Version

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