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CDK4 cyclin dependent kinase 4 [ Eptesicus fuscus (big brown bat) ]

Gene ID: 103292479, updated on 30-Mar-2024

Summary

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Gene symbol
CDK4
Gene description
cyclin dependent kinase 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Eptesicus fuscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Eptesicus
Orthologs
human mouse all
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Genomic context

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See CDK4 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_03 current DD_ASM_mEF_20220401 (GCF_027574615.1) 7 NC_072479.1 (52349345..52352387)
101 previous assembly EptFus1.0 (GCF_000308155.1) Unplaced Scaffold NW_007370699.1 (2062244..2076549, complement)

Chromosome 7 - NC_072479.1Genomic Context describing neighboring genes Neighboring gene 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial Neighboring gene membrane associated ring-CH-type finger 9 Neighboring gene tetraspanin 31 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Neighboring gene OS9 endoplasmic reticulum lectin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027574615.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference DD_ASM_mEF_20220401

Genomic

  1. NC_072479.1 Reference DD_ASM_mEF_20220401

    Range
    52349345..52352387
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054718925.1 → XP_054574900.1  cyclin-dependent kinase 4 isoform X1

  2. XM_054718926.1 → XP_054574901.1  cyclin-dependent kinase 4 isoform X2

  3. XM_008148724.3 → XP_008146946.1  cyclin-dependent kinase 4 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:5 → 295
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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