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CRKL CRK like proto-oncogene, adaptor protein [ Eptesicus fuscus (big brown bat) ]

Gene ID: 103286991, updated on 30-Mar-2024

Summary

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Gene symbol
CRKL
Gene description
CRK like proto-oncogene, adaptor protein
Gene type
protein coding
RefSeq status
MODEL
Organism
Eptesicus fuscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Eptesicus
Orthologs
human mouse all
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Genomic context

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See CRKL in Genome Data Viewer
Location:
chromosome: 23
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_03 current DD_ASM_mEF_20220401 (GCF_027574615.1) 23 NC_072495.1 (12615987..12641156)
101 previous assembly EptFus1.0 (GCF_000308155.1) Unplaced Scaffold NW_007370668.1 (13573619..13598868, complement)

Chromosome 23 - NC_072495.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 29 Neighboring gene small nucleolar RNA SNORA43 Neighboring gene U6 spliceosomal RNA Neighboring gene AIF family member 3 Neighboring gene leucine zipper like post translational regulator 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
crk-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027574615.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference DD_ASM_mEF_20220401

Genomic

  1. NC_072495.1 Reference DD_ASM_mEF_20220401

    Range
    12615987..12641156
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008142633.3 → XP_008140855.1  crk-like protein

    Conserved Domains (3) summary
    cd09926
    Location:6 → 106
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:126 → 180
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:237 → 293
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
Nucleotide Protein
Heading Accession and Version

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