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SMG6 SMG6 nonsense mediated mRNA decay factor [ Carlito syrichta (Philippine tarsier) ]

Gene ID: 103260576, updated on 11-Mar-2024

Summary

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Gene symbol
SMG6
Gene description
SMG6 nonsense mediated mRNA decay factor
See related
Ensembl:ENSTSYG00000003406
Gene type
protein coding
RefSeq status
MODEL
Organism
Carlito syrichta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Tarsiiformes; Tarsiidae; Carlito
Orthologs
human mouse all
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Genomic context

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See SMG6 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
101 current Tarsius_syrichta-2.0.1 (GCF_000164805.1) Unplaced Scaffold NW_007247343.1 (242398..502293)

NW_007247343.1Genomic Context describing neighboring genes Neighboring gene small G protein signaling modulator 2 Neighboring gene TSR1 ribosome maturation factor Neighboring gene serine racemase Neighboring gene 40S ribosomal protein S11-like Neighboring gene HIC ZBTB transcriptional repressor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007247343 Unplaced Scaffold Reference Tarsius_syrichta-2.0.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomerase RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of telomerase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
telomerase-binding protein EST1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Carlito syrichta Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tarsius_syrichta-2.0.1 Primary Assembly

Genomic

  1. NW_007247343.1 Reference Tarsius_syrichta-2.0.1 Primary Assembly

    Range
    242398..502293
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008058210.2 → XP_008056401.1  telomerase-binding protein EST1A isoform X1

    UniProtKB/TrEMBL
    A0A1U7TRN8
    Related
    ENSTSYP00000003134.2, ENSTSYT00000003426.2
    Conserved Domains (4) summary
    cd09885
    Location:1241 → 1416
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    pfam10373
    Location:751 → 1103
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:638 → 741
    EST1; Telomerase activating protein Est1
    pfam12868
    Location:480 → 553
    DUF3824; Domain of unknwon function (DUF3824)

  2. XM_008058211.2 → XP_008056402.1  telomerase-binding protein EST1A isoform X2

    See identical proteins and their annotated locations for XP_008056402.1

    UniProtKB/TrEMBL
    A0A1U7TTK5
    Related
    ENSTSYP00000034364.1, ENSTSYT00000047594.1
    Conserved Domains (2) summary
    cd09885
    Location:333 → 508
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    pfam10373
    Location:1 → 195
    EST1_DNA_bind; Est1 DNA/RNA binding domain

  3. XM_008058212.2 → XP_008056403.1  telomerase-binding protein EST1A isoform X2

    See identical proteins and their annotated locations for XP_008056403.1

    UniProtKB/TrEMBL
    A0A1U7TTK5
    Conserved Domains (2) summary
    cd09885
    Location:333 → 508
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    pfam10373
    Location:1 → 195
    EST1_DNA_bind; Est1 DNA/RNA binding domain
Nucleotide Protein
Heading Accession and Version

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