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PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Carlito syrichta (Philippine tarsier) ]

Gene ID: 103255490, updated on 11-Mar-2024

Summary

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Gene symbol
PFKFB1
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
See related
Ensembl:ENSTSYG00000005596
Gene type
protein coding
RefSeq status
MODEL
Organism
Carlito syrichta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Tarsiiformes; Tarsiidae; Carlito
Orthologs
human mouse all
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Genomic context

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See PFKFB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Tarsius_syrichta-2.0.1 (GCF_000164805.1) Unplaced Scaffold NW_007232271.1 (42886..94368)

NW_007232271.1Genomic Context describing neighboring genes Neighboring gene 5'-aminolevulinate synthase 2 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene trophinin

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007232271 Unplaced Scaffold Reference Tarsius_syrichta-2.0.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Carlito syrichta Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tarsius_syrichta-2.0.1 Primary Assembly

Genomic

  1. NW_007232271.1 Reference Tarsius_syrichta-2.0.1 Primary Assembly

    Range
    42886..94368
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008053463.2 → XP_008051654.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A1U7SUX2
    Related
    ENSTSYP00000031580.1, ENSTSYT00000042191.1
    Conserved Domains (2) summary
    pfam00300
    Location:189 → 372
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:7 → 186
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_008053461.1 → XP_008051652.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A1U7TFA0
    Related
    ENSTSYP00000015489.1, ENSTSYT00000028147.1
    Conserved Domains (3) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:29 → 250
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:43 → 197
    AAA_33; AAA domain

  3. XM_008053462.1 → XP_008051653.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A1U7T5J9
    Conserved Domains (3) summary
    pfam00300
    Location:231 → 414
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:29 → 228
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:43 → 175
    AAA_33; AAA domain
Nucleotide Protein
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