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PLCB1 phospholipase C beta 1 [ Chlorocebus sabaeus (green monkey) ]

Gene ID: 103246657, updated on 11-Mar-2024

Summary

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Gene symbol
PLCB1
Gene description
phospholipase C beta 1
See related
Ensembl:ENSCSAG00000013586
Gene type
protein coding
RefSeq status
MODEL
Organism
Chlorocebus sabaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
35
Annotation release Status Assembly Chr Location
102 current Vero_WHO_p1.0 (GCF_015252025.1) Unplaced Scaffold NW_023666071.1 (14560873..15334958)
100 previous assembly Chlorocebus_sabeus 1.1 (GCF_000409795.2) 2 NC_023643.1 (29242601..29994238, complement)

NW_023666071.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103246674 Neighboring gene 40S ribosomal protein SA-like Neighboring gene thioredoxin related transmembrane protein 4 Neighboring gene uncharacterized LOC119621491 Neighboring gene long-chain-fatty-acid--CoA ligase 4-like Neighboring gene small nucleolar RNA SNORA73 family Neighboring gene phospholipase C beta 4 Neighboring gene uncharacterized LOC103246578

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in memory IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chlorocebus sabaeus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Vero_WHO_p1.0

Genomic

  1. NW_023666071.1 Reference Vero_WHO_p1.0

    Range
    14560873..15334958
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008018395.2 → XP_008016586.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2

    UniProtKB/TrEMBL
    A0A0D9RMA8
    Conserved Domains (5) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1141
    PLC-beta_C; PLC-beta C terminal

  2. XM_008018384.2 → XP_008016575.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1

    UniProtKB/TrEMBL
    A0A0D9RMA8
    Conserved Domains (5) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1172
    PLC-beta_C; PLC-beta C terminal

  3. XM_037990865.1 → XP_037846793.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2

    UniProtKB/TrEMBL
    A0A0D9RMA8
    Conserved Domains (5) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1141
    PLC-beta_C; PLC-beta C terminal

  4. XM_008018403.2 → XP_008016594.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X3

    UniProtKB/TrEMBL
    A0A0D9RMA8
    Conserved Domains (5) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1142
    PLC-beta_C; PLC-beta C terminal
Nucleotide Protein
Heading Accession and Version

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