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PLCZ1 phospholipase C zeta 1 [ Chlorocebus sabaeus (green monkey) ]

Gene ID: 103218714, updated on 11-Mar-2024

Summary

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Gene symbol
PLCZ1
Gene description
phospholipase C zeta 1
See related
Ensembl:ENSCSAG00000008141
Gene type
protein coding
RefSeq status
MODEL
Organism
Chlorocebus sabaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus
Orthologs
human mouse all
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Genomic context

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See PLCZ1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current Vero_WHO_p1.0 (GCF_015252025.1) Unplaced Scaffold NW_023666069.1 (16626501..16679788)
100 previous assembly Chlorocebus_sabeus 1.1 (GCF_000409795.2) 11 NC_023652.1 (18534672..18587756, complement)

NW_023666069.1Genomic Context describing neighboring genes Neighboring gene BLOC-1-related complex subunit 8-like Neighboring gene capping actin protein of muscle Z-line subunit alpha 3 Neighboring gene phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma Neighboring gene zinc finger CCHC domain-containing protein 9-like Neighboring gene dnaJ homolog subfamily C member 8-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytosolic calcium ion concentration involved in egg activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chlorocebus sabaeus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Vero_WHO_p1.0

Genomic

  1. NW_023666069.1 Reference Vero_WHO_p1.0

    Range
    16626501..16679788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007967800.2 → XP_007965991.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X1

    UniProtKB/TrEMBL
    A0A0D9R6Y3
    Related
    ENSCSAP00000004372.1
    Conserved Domains (4) summary
    cd00275
    Location:481 → 606
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08595
    Location:154 → 452
    PI-PLCc_zeta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-zeta
    PLN02952
    Location:71 → 607
    PLN02952; phosphoinositide phospholipase C
    pfam09279
    Location:72 → 154
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like

  2. XM_007967801.2 → XP_007965992.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X2

    UniProtKB/TrEMBL
    A0A0D9R6Y3
    Conserved Domains (3) summary
    cd00275
    Location:377 → 502
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08595
    Location:50 → 348
    PI-PLCc_zeta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-zeta
    pfam09279
    Location:1 → 50
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like

  3. XM_037990305.1 → XP_037846233.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X3

    Conserved Domains (4) summary
    PLN02952
    Location:44 → 414
    PLN02952; phosphoinositide phospholipase C
    cd15898
    Location:1 → 32
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:1 → 48
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl14615
    Location:35 → 259
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
Nucleotide Protein
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