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lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) [ Callorhinchus milii (elephant shark) ]

Gene ID: 103188931, updated on 11-Mar-2024

Summary

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Gene symbol
lss
Gene description
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
See related
Ensembl:ENSCMIG00000015372
Gene type
protein coding
RefSeq status
MODEL
Organism
Callorhinchus milii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus
Orthologs
human zebrafish all
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Genomic context

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See lss in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
101 current IMCB_Cmil_1.0 (GCF_018977255.1) Unplaced Scaffold NW_024704747.1 (10994020..11018562, complement)
100 previous assembly Callorhinchus_milii-6.1.3 (GCF_000165045.1) Unplaced Scaffold NW_006890292.1 (285000..308933, complement)

NW_024704747.1Genomic Context describing neighboring genes Neighboring gene spermatogenesis and centriole associated 1 like Neighboring gene formimidoyltransferase cyclodeaminase Neighboring gene pericentrin Neighboring gene minichromosome maintenance complex component 3 associated protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequencing and analysis of full-length cDNAs, 5'-ESTs and 3'-ESTs from a cartilaginous fish, the elephant shark (Callorhinchus milii). Tan YY, et al. PLoS One, 2012. PMID 23056606, Free PMC Article
  2. Elephant shark genome provides unique insights into gnathostome evolution. Venkatesh B, et al. Nature, 2014 Jan 9. PMID 24402279, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables lanosterol synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triterpenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lanosterol synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Callorhinchus milii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference IMCB_Cmil_1.0 Primary Assembly

Genomic

  1. NW_024704747.1 Reference IMCB_Cmil_1.0 Primary Assembly

    Range
    10994020..11018562 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007909122.2 → XP_007907313.2  lanosterol synthase

    UniProtKB/TrEMBL
    A0A4W3JF24
    Conserved Domains (1) summary
    cd02892
    Location:74 → 716
    SQCY_1; Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization ...
Nucleotide Protein
Heading Accession and Version

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