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PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Python bivittatus (Burmese python) ]

Gene ID: 103058033, updated on 11-Mar-2024

Summary

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Gene symbol
PFKFB1
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Python bivittatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Henophidia; Pythonidae; Python
Orthologs
human mouse all
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Genomic context

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See PFKFB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
102 current Python_molurus_bivittatus-5.0.2 (GCF_000186305.1) Unplaced Scaffold NW_006532187.1 (161586..182883, complement)

NW_006532187.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 120 member C Neighboring gene PHD finger protein 8 Neighboring gene inter-alpha-trypsin inhibitor heavy chain family member 6 Neighboring gene non-structural maintenance of chromosomes element 3 homolog Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene 5'-aminolevulinate synthase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006532187 Unplaced Scaffold Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Python bivittatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Genomic

  1. NW_006532187.1 Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

    Range
    161586..182883 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025176777.1 → XP_025032545.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X4

    UniProtKB/TrEMBL
    A0A9F2Q342
    Conserved Domains (2) summary
    pfam01591
    Location:28 → 250
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:253 → 439
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  2. XM_025176761.1 → XP_025032529.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A9F2QVY5
    Conserved Domains (2) summary
    pfam01591
    Location:28 → 250
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:253 → 439
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  3. XM_025176764.1 → XP_025032532.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A9F5J4Q4
    Conserved Domains (2) summary
    pfam01591
    Location:11 → 229
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:232 → 418
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  4. XM_007422198.2 → XP_007422260.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X5

    UniProtKB/TrEMBL
    A0A9F2KTY7
    Conserved Domains (3) summary
    pfam00300
    Location:232 → 415
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:11 → 229
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:21 → 176
    AAA_33; AAA domain

  5. XM_007422194.2 → XP_007422256.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A9F2QVY5
    Conserved Domains (2) summary
    pfam01591
    Location:28 → 250
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:253 → 439
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  6. XM_007422197.2 → XP_007422259.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X4

    UniProtKB/TrEMBL
    A0A9F2Q342
    Conserved Domains (2) summary
    pfam01591
    Location:28 → 250
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:253 → 439
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  7. XM_025176768.1 → XP_025032536.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A9F5JF86
    Conserved Domains (2) summary
    pfam01591
    Location:1 → 209
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:212 → 398
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
Nucleotide Protein
Heading Accession and Version

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