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TLR1 toll like receptor 1 [ Physeter catodon (sperm whale) ]

Gene ID: 102982833, updated on 10-Mar-2024

Summary

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Gene symbol
TLR1
Gene description
toll like receptor 1
See related
Ensembl:ENSPCTG00005017458
Gene type
protein coding
RefSeq status
MODEL
Organism
Physeter catodon
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Physeteridae; Physeter
Orthologs
human mouse all
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Genomic context

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See TLR1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_04 current ASM283717v5 (GCF_002837175.3) 7 NC_041220.1 (80108249..80149709)
102 previous assembly ASM283717v2 (GCF_002837175.2) 7 NC_041220.1 (80108278..80149709)

Chromosome 7 - NC_041220.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 156 Neighboring gene family with sequence similarity 114 member A1 Neighboring gene toll like receptor 6 Neighboring gene toll like receptor 10 Neighboring gene transfer RNA glycine (anticodon ACC)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Toll-like receptor 2 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipopeptide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to triacyl bacterial lipopeptide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Toll-like receptor 1-Toll-like receptor 2 protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
toll-like receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002837175.3-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM283717v5 Primary Assembly

Genomic

  1. NC_041220.1 Reference ASM283717v5 Primary Assembly

    Range
    80108249..80149709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024117856.3 → XP_023973624.1  toll-like receptor 1

    UniProtKB/TrEMBL
    A0A2Y9S8H7
    Conserved Domains (6) summary
    PRK15370
    Location:347 → 505
    PRK15370; E3 ubiquitin-protein ligase SlrP; Provisional
    smart00082
    Location:527 → 580
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:639 → 782
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:43 → 448
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:51 → 74
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:353 → 376
    LRR_RI; leucine-rich repeat [structural motif]

  2. XM_024117853.3 → XP_023973621.1  toll-like receptor 1

    UniProtKB/TrEMBL
    A0A2Y9S8H7
    Conserved Domains (6) summary
    PRK15370
    Location:347 → 505
    PRK15370; E3 ubiquitin-protein ligase SlrP; Provisional
    smart00082
    Location:527 → 580
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:639 → 782
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:43 → 448
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:51 → 74
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:353 → 376
    LRR_RI; leucine-rich repeat [structural motif]

  3. XM_055086099.1 → XP_054942074.1  toll-like receptor 1

    UniProtKB/TrEMBL
    A0A2Y9S8H7

  4. XM_028492057.1 → XP_028347858.1  toll-like receptor 1

    UniProtKB/TrEMBL
    A0A2Y9S8H7
    Conserved Domains (6) summary
    PRK15370
    Location:347 → 505
    PRK15370; E3 ubiquitin-protein ligase SlrP; Provisional
    smart00082
    Location:527 → 580
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:639 → 782
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:43 → 448
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:51 → 74
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:353 → 376
    LRR_RI; leucine-rich repeat [structural motif]

  5. XM_024117849.2 → XP_023973617.1  toll-like receptor 1

    UniProtKB/TrEMBL
    A0A2Y9S8H7
    Conserved Domains (6) summary
    PRK15370
    Location:347 → 505
    PRK15370; E3 ubiquitin-protein ligase SlrP; Provisional
    smart00082
    Location:527 → 580
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:639 → 782
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:43 → 448
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:51 → 74
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:353 → 376
    LRR_RI; leucine-rich repeat [structural motif]

  6. XM_028492058.1 → XP_028347859.1  toll-like receptor 1

    UniProtKB/TrEMBL
    A0A2Y9S8H7
    Conserved Domains (6) summary
    PRK15370
    Location:347 → 505
    PRK15370; E3 ubiquitin-protein ligase SlrP; Provisional
    smart00082
    Location:527 → 580
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:639 → 782
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:43 → 448
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:51 → 74
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:353 → 376
    LRR_RI; leucine-rich repeat [structural motif]

  7. XM_024117871.3 → XP_023973639.1  toll-like receptor 1

    UniProtKB/TrEMBL
    A0A2Y9S8H7
    Conserved Domains (6) summary
    PRK15370
    Location:347 → 505
    PRK15370; E3 ubiquitin-protein ligase SlrP; Provisional
    smart00082
    Location:527 → 580
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:639 → 782
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:43 → 448
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:51 → 74
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:353 → 376
    LRR_RI; leucine-rich repeat [structural motif]

  8. XM_024117864.2 → XP_023973632.1  toll-like receptor 1

    UniProtKB/TrEMBL
    A0A2Y9S8H7
    Related
    ENSPCTP00005024297.1, ENSPCTT00005026780.1
    Conserved Domains (6) summary
    PRK15370
    Location:347 → 505
    PRK15370; E3 ubiquitin-protein ligase SlrP; Provisional
    smart00082
    Location:527 → 580
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:639 → 782
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:43 → 448
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:51 → 74
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:353 → 376
    LRR_RI; leucine-rich repeat [structural motif]
Nucleotide Protein
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