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NPL N-acetylneuraminate pyruvate lyase [ Panthera tigris (tiger) ]

Gene ID: 102964881, updated on 10-Mar-2024

Summary

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Gene symbol
NPL
Gene description
N-acetylneuraminate pyruvate lyase
See related
Ensembl:ENSPTIG00000019669
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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See NPL in Genome Data Viewer
Location:
chromosome: F3
Exon count:
13
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) F3 NC_056678.1 (25493464..25531531, complement)

Chromosome F3 - NC_056678.1Genomic Context describing neighboring genes Neighboring gene SHC binding and spindle associated 1 like Neighboring gene DExH-box helicase 9 Neighboring gene uncharacterized LOC122235845 Neighboring gene uncharacterized LOC122235846 Neighboring gene regulator of G protein signaling 8 Neighboring gene uncharacterized LOC122235940

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056678.1 Chromosome F3 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 4-hydroxy-tetrahydrodipicolinate synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables N-acetylneuraminate lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in N-acetylneuraminate catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
N-acetylneuraminate lyase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056678.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    25493464..25531531 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015543848.2 → XP_015399334.1  N-acetylneuraminate lyase isoform X2

    Conserved Domains (1) summary
    cl21457
    Location:8 → 270
    TIM_phosphate_binding; TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate ...

  2. XM_007096211.2 → XP_007096273.1  N-acetylneuraminate lyase isoform X1

    UniProtKB/TrEMBL
    A0A8C9MCV7
    Related
    ENSPTIP00000023099.1
    Conserved Domains (1) summary
    cd00954
    Location:8 → 301
    NAL; N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL)

  3. XM_042976154.1 → XP_042832088.1  N-acetylneuraminate lyase isoform X1

    UniProtKB/TrEMBL
    A0A8C9MCV7
    Conserved Domains (1) summary
    cd00954
    Location:8 → 301
    NAL; N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL)

  4. XM_007096212.2 → XP_007096274.1  N-acetylneuraminate lyase isoform X3

    UniProtKB/TrEMBL
    A0A8C9KT23
    Related
    ENSPTIP00000023104.1
    Conserved Domains (1) summary
    cl21457
    Location:8 → 218
    TIM; TIM-like beta/alpha barrel domains
Nucleotide Protein
Heading Accession and Version

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