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TMTC4 transmembrane O-mannosyltransferase targeting cadherins 4 [ Panthera tigris (tiger) ]

Gene ID: 102960589, updated on 10-Mar-2024

Summary

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Gene symbol
TMTC4
Gene description
transmembrane O-mannosyltransferase targeting cadherins 4
See related
Ensembl:ENSPTIG00000009014
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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See TMTC4 in Genome Data Viewer
Location:
chromosome: A1
Exon count:
19
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) A1 NC_056660.1 (71031339..71095937, complement)

Chromosome A1 - NC_056660.1Genomic Context describing neighboring genes Neighboring gene propionyl-CoA carboxylase subunit alpha Neighboring gene 39S ribosomal protein L47, mitochondrial-like Neighboring gene formin-like protein 16 Neighboring gene uncharacterized LOC122237032 Neighboring gene U6 spliceosomal RNA Neighboring gene gamma-glutamylamine cyclotransferase Neighboring gene small nucleolar RNA SNORA72 Neighboring gene sodium leak channel, non-selective

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056660.1 Chromosome A1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein O-mannosyl-transferase TMTC4
Names
transmembrane and tetratricopeptide repeat containing 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056660.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    71031339..71095937 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042979763.1 → XP_042835697.1  protein O-mannosyl-transferase TMTC4 isoform X1

    UniProtKB/TrEMBL
    A0A8C9M5D6
    Conserved Domains (3) summary
    COG0457
    Location:450 → 713
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:482 → 510
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:294 → 366
    DUF1736; Domain of unknown function (DUF1736)

  2. XM_042979764.1 → XP_042835698.1  protein O-mannosyl-transferase TMTC4 isoform X2

    UniProtKB/TrEMBL
    A0A8C9JWS5, A0A8C9M5D6
    Conserved Domains (3) summary
    COG0457
    Location:449 → 712
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:481 → 509
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:293 → 365
    DUF1736; Domain of unknown function (DUF1736)

  3. XM_042979759.1 → XP_042835693.1  protein O-mannosyl-transferase TMTC4 isoform X1

    UniProtKB/TrEMBL
    A0A8C9M5D6
    Conserved Domains (3) summary
    COG0457
    Location:450 → 713
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:482 → 510
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:294 → 366
    DUF1736; Domain of unknown function (DUF1736)
Nucleotide Protein
Heading Accession and Version

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