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HIF3A hypoxia inducible factor 3 subunit alpha [ Chelonia mydas (Green sea turtle) ]

Gene ID: 102946043, updated on 10-Mar-2024

Summary

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Gene symbol
HIF3A
Gene description
hypoxia inducible factor 3 subunit alpha
Locus tag
UY3_15846
See related
EnsemblRapid:ENSCMYG00015004908
Gene type
protein coding
RefSeq status
MODEL
Organism
Chelonia mydas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Cheloniidae; Chelonia
Orthologs
human mouse all
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Genomic context

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See HIF3A in Genome Data Viewer
Location:
chromosome: 23
Exon count:
18
Annotation release Status Assembly Chr Location
103 current rCheMyd1.pri.v2 (GCF_015237465.2) 23 NC_051263.2 (5394558..5418069, complement)
102 previous assembly rCheMyd1.pri (GCF_015237465.1) 23 NC_051263.1 (4559126..4580853)

Chromosome 23 - NC_051263.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114021592 Neighboring gene protein phosphatase 5 catalytic subunit Neighboring gene adenosine receptor A1 Neighboring gene small nuclear ribonucleoprotein D2 polypeptide

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers. Duffy DJ, et al. Commun Biol, 2018. PMID 30271945, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to hypoxia IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hypoxia-inducible factor 3-alpha
Names
Hypoxia-inducible factor 3-alpha
hypoxia inducible factor 3 alpha subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chelonia mydas Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rCheMyd1.pri.v2 Primary Assembly

Genomic

  1. NC_051263.2 Reference rCheMyd1.pri.v2 Primary Assembly

    Range
    5394558..5418069 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037884652.2 → XP_037740580.1  hypoxia-inducible factor 3-alpha isoform X4

    Related
    ENSCMYP00015007580.1, ENSCMYT00015009178.1
    Conserved Domains (4) summary
    smart00091
    Location:89 → 148
    PAS; PAS domain
    cd19729
    Location:14 → 76
    bHLH-PAS_HIF3a_PASD7; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in hypoxia-inducible factor 3-alpha (HIF3a) and similar proteins
    pfam11413
    Location:498 → 527
    HIF-1; Hypoxia-inducible factor-1
    pfam14598
    Location:240 → 345
    PAS_11; PAS domain

  2. XM_043534708.1 → XP_043390643.1  hypoxia-inducible factor 3-alpha isoform X3

    Conserved Domains (3) summary
    smart00091
    Location:89 → 148
    PAS; PAS domain
    pfam08447
    Location:250 → 337
    PAS_3; PAS fold
    cd19729
    Location:14 → 76
    bHLH-PAS_HIF3a_PASD7; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in hypoxia-inducible factor 3-alpha (HIF3a) and similar proteins

  3. XM_043534707.1 → XP_043390642.1  hypoxia-inducible factor 3-alpha isoform X2

    Related
    ENSCMYP00015007576.1, ENSCMYT00015009172.1
    Conserved Domains (4) summary
    smart00091
    Location:128 → 187
    PAS; PAS domain
    cd19729
    Location:53 → 115
    bHLH-PAS_HIF3a_PASD7; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in hypoxia-inducible factor 3-alpha (HIF3a) and similar proteins
    pfam11413
    Location:537 → 566
    HIF-1; Hypoxia-inducible factor-1
    pfam14598
    Location:279 → 384
    PAS_11; PAS domain

  4. XM_043534706.1 → XP_043390641.1  hypoxia-inducible factor 3-alpha isoform X1

    Conserved Domains (3) summary
    smart00091
    Location:128 → 187
    PAS; PAS domain
    pfam08447
    Location:289 → 376
    PAS_3; PAS fold
    cd19729
    Location:53 → 115
    bHLH-PAS_HIF3a_PASD7; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in hypoxia-inducible factor 3-alpha (HIF3a) and similar proteins

  5. XM_043534709.1 → XP_043390644.1  hypoxia-inducible factor 3-alpha isoform X5

    Conserved Domains (3) summary
    smart00091
    Location:31 → 90
    PAS; PAS domain
    pfam08447
    Location:192 → 279
    PAS_3; PAS fold
    cl00081
    Location:1 → 18
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  6. XM_043534710.1 → XP_043390645.1  hypoxia-inducible factor 3-alpha isoform X5

    Conserved Domains (3) summary
    smart00091
    Location:31 → 90
    PAS; PAS domain
    pfam08447
    Location:192 → 279
    PAS_3; PAS fold
    cl00081
    Location:1 → 18
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
Nucleotide Protein
Heading Accession and Version

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