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SETX senataxin [ Chelonia mydas (Green sea turtle) ]

Gene ID: 102941265, updated on 10-Mar-2024

Summary

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Gene symbol
SETX
Gene description
senataxin
Locus tag
UY3_08237
See related
EnsemblRapid:ENSCMYG00015003493
Gene type
protein coding
RefSeq status
MODEL
Organism
Chelonia mydas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Cheloniidae; Chelonia
Orthologs
human mouse all
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Genomic context

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See SETX in Genome Data Viewer
Location:
chromosome: 16
Exon count:
30
Annotation release Status Assembly Chr Location
103 current rCheMyd1.pri.v2 (GCF_015237465.2) 16 NC_057857.1 (15570138..15618985, complement)
102 previous assembly rCheMyd1.pri (GCF_015237465.1) 16 NC_051256.1 (15569512..15618942, complement)

Chromosome 16 - NC_057857.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC122463111 Neighboring gene netrin G2 Neighboring gene uncharacterized LOC122463101 Neighboring gene transcription termination factor 1 Neighboring gene cilia and flagella associated protein 77

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers. Duffy DJ, et al. Commun Biol, 2018. PMID 30271945, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription termination site sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in termination of RNA polymerase II transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear body IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
probable helicase senataxin
Names
Putative helicase senataxin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chelonia mydas Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rCheMyd1.pri.v2 Primary Assembly

Genomic

  1. NC_057857.1 Reference rCheMyd1.pri.v2 Primary Assembly

    Range
    15570138..15618985 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_043530068.1 → XP_043386003.1  probable helicase senataxin isoform X3

    UniProtKB/TrEMBL
    M7BGB8
    Conserved Domains (4) summary
    cd18042
    Location:2101 → 2426
    DEXXQc_SETX; DEXXQ-box helicase domain of SETX
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    pfam13087
    Location:2392 → 2610
    AAA_12; AAA domain
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  2. XM_037879985.2 → XP_037735913.1  probable helicase senataxin isoform X3

    UniProtKB/TrEMBL
    M7BGB8
    Conserved Domains (4) summary
    cd18042
    Location:2101 → 2426
    DEXXQc_SETX; DEXXQ-box helicase domain of SETX
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    pfam13087
    Location:2392 → 2610
    AAA_12; AAA domain
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  3. XM_037879986.2 → XP_037735914.1  probable helicase senataxin isoform X3

    UniProtKB/TrEMBL
    M7BGB8
    Conserved Domains (4) summary
    cd18042
    Location:2101 → 2426
    DEXXQc_SETX; DEXXQ-box helicase domain of SETX
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    pfam13087
    Location:2392 → 2610
    AAA_12; AAA domain
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  4. XM_037879987.2 → XP_037735915.1  probable helicase senataxin isoform X3

    UniProtKB/TrEMBL
    M7BGB8
    Conserved Domains (4) summary
    cd18042
    Location:2101 → 2426
    DEXXQc_SETX; DEXXQ-box helicase domain of SETX
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    pfam13087
    Location:2392 → 2610
    AAA_12; AAA domain
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  5. XM_037879989.2 → XP_037735917.1  probable helicase senataxin isoform X6

    UniProtKB/TrEMBL
    M7BGB8
    Related
    ENSCMYP00015005346.1, ENSCMYT00015006494.1
    Conserved Domains (4) summary
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    pfam13087
    Location:2306 → 2524
    AAA_12; AAA domain
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    cl28899
    Location:2101 → 2340
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

  6. XM_037879988.2 → XP_037735916.1  probable helicase senataxin isoform X4

    UniProtKB/TrEMBL
    M7BGB8
    Conserved Domains (4) summary
    cd18042
    Location:2101 → 2376
    DEXXQc_SETX; DEXXQ-box helicase domain of SETX
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    pfam13087
    Location:2342 → 2560
    AAA_12; AAA domain
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  7. XM_043530069.1 → XP_043386004.1  probable helicase senataxin isoform X5

    UniProtKB/TrEMBL
    M7BGB8
    Related
    ENSCMYP00015005341.1, ENSCMYT00015006489.1
    Conserved Domains (2) summary
    cd18808
    Location:2391 → 2573
    SF1_C_Upf1; C-terminal helicase domain of Upf1-like family helicases
    cd18042
    Location:2101 → 2390
    DEXXQc_SETX; DEXXQ-box helicase domain of SETX

  8. XM_037879983.2 → XP_037735911.1  probable helicase senataxin isoform X2

    UniProtKB/TrEMBL
    M7BGB8
    Conserved Domains (4) summary
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    pfam13086
    Location:2104 → 2352
    AAA_11; AAA domain
    pfam13087
    Location:2356 → 2574
    AAA_12; AAA domain
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  9. XM_037879990.2 → XP_037735918.1  probable helicase senataxin isoform X7

    UniProtKB/TrEMBL
    M7BGB8
    Conserved Domains (4) summary
    COG1112
    Location:2056 → 2543
    DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]
    cd18042
    Location:2101 → 2426
    DEXXQc_SETX; DEXXQ-box helicase domain of SETX
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  10. XM_037879982.2 → XP_037735910.1  probable helicase senataxin isoform X1

    UniProtKB/TrEMBL
    M7BGB8
    Related
    ENSCMYP00015005337.1, ENSCMYT00015006485.1
    Conserved Domains (4) summary
    cd18042
    Location:2101 → 2426
    DEXXQc_SETX; DEXXQ-box helicase domain of SETX
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    pfam13087
    Location:2392 → 2590
    AAA_12; AAA domain
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  11. XM_043530071.1 → XP_043386006.1  probable helicase senataxin isoform X8

    UniProtKB/TrEMBL
    M7BGB8
    Conserved Domains (2) summary
    TIGR00376
    Location:2053 → 2313
    TIGR00376; DNA helicase, putative
    cl28899
    Location:2101 → 2349
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

  12. XM_037879991.2 → XP_037735919.1  probable helicase senataxin isoform X9

    UniProtKB/TrEMBL
    M7BGB8
    Conserved Domains (4) summary
    TIGR00376
    Location:2053 → 2291
    TIGR00376; DNA helicase, putative
    pfam12726
    Location:38 → 354
    SEN1_N; SEN1 N terminal
    NF033845
    Location:1063 → 1293
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    cl28899
    Location:2101 → 2218
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
Nucleotide Protein
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