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OAS2 2'-5'-oligoadenylate synthetase 2 [ Felis catus (domestic cat) ]

Gene ID: 102902426, updated on 17-Aug-2024

Summary

Official Symbol
OAS2
Official Full Name
2'-5'-oligoadenylate synthetase 2
Primary source
VGNC:VGNC:68607
See related
EnsemblRapid:ENSFCTG00005014509
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
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Genomic context

See OAS2 in Genome Data Viewer
Location:
chromosome: D3
Exon count:
11
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) D3 NC_058379.1 (10598248..10617610)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) D3 NC_018734.3 (10722893..10742441)

Chromosome D3 - NC_058379.1Genomic Context describing neighboring genes Neighboring gene 2'-5'-oligoadenylate synthetase 1 Neighboring gene 2'-5'-oligoadenylate synthetase 3 Neighboring gene uncharacterized LOC123381100 Neighboring gene uncharacterized LOC102902475

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2'-5'-oligoadenylate synthetase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of viral genome replication IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of ribonuclease activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
2'-5'-oligoadenylate synthase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058379.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    10598248..10617610
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045041130.1XP_044897065.1  2'-5'-oligoadenylate synthase 2 isoform X1

    UniProtKB/TrEMBL
    A0A5F5XD60
    Conserved Domains (1) summary
    cd05400
    Location:364510
    NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
  2. XM_006938494.5XP_006938556.1  2'-5'-oligoadenylate synthase 2 isoform X2

    UniProtKB/TrEMBL
    A0A5F5XD60, M3VUJ0
    Related
    ENSFCTP00005029596.1, ENSFCTT00005041682.1
    Conserved Domains (2) summary
    cd05400
    Location:361507
    NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
    pfam10421
    Location:494681
    OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus