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topA DNA topoisomerase I [ Methanobacterium lacus ]

Gene ID: 10276978, updated on 22-Oct-2024

Summary

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Gene symbol
topA
Gene description
DNA topoisomerase I
Locus tag
METBO_RS02730
Gene type
protein coding
Organism
Methanobacterium lacus (strain: AL-21)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Methanomada group; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanobacterium
Old locus tag
Metbo_0533
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Genomic context

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Sequence:
NC_015216.1 (521181..523508)

NC_015216.1Genomic Context describing neighboring genes Neighboring gene RlmE family RNA methyltransferase Neighboring gene metallophosphoesterase Neighboring gene STT3 domain-containing protein Neighboring gene GTP-binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_015216.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Methanobacterium paludis sp. nov. and a novel strain of Methanobacterium lacus isolated from northern peatlands. Cadillo-Quiroz H, et al. Int J Syst Evol Microbiol, 2014 May. PMID 24449792

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
DNA topoisomerase I
WP_013644136.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_015216.1 Reference assembly

    Range
    521181..523508
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_013644136.1 DNA topoisomerase I [Methanobacterium lacus]

    See identical proteins and their annotated locations for WP_013644136.1

    UniProtKB/TrEMBL
    F0T9W2
    Conserved Domains (5) summary
    COG0551
    Location:578 → 711
    YrdD; ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1 [Replication, recombination and repair]
    cd00186
    Location:156 → 569
    TOP1Ac; DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA ...
    TIGR01057
    Location:6 → 622
    topA_arch; DNA topoisomerase I, archaeal
    pfam01396
    Location:674 → 710
    zf-C4_Topoisom; Topoisomerase DNA binding C4 zinc finger
    cl00718
    Location:4 → 151
    TOPRIM; Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from ...
Nucleotide Protein
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