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CAPN3 calpain 3 [ Leptonychotes weddellii (Weddell seal) ]

Gene ID: 102746966, updated on 10-Mar-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Leptonychotes weddellii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Leptonychotes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
101 current LepWed1.0 (GCF_000349705.1) Unplaced Scaffold NW_006383351.1 (1178439..1198554, complement)

NW_006383351.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 23 Neighboring gene zinc finger protein 106 Neighboring gene calpain-3-like Neighboring gene uncharacterized LOC115940389 Neighboring gene uncharacterized LOC115940388 Neighboring gene glucosidase alpha, neutral C

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006383351 Unplaced Scaffold Reference LepWed1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Leptonychotes weddellii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LepWed1.0 Primary Assembly

Genomic

  1. NW_006383351.1 Reference LepWed1.0 Primary Assembly

    Range
    1178439..1198554 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031026406.1 → XP_030882266.1  calpain-3 isoform X6

    UniProtKB/TrEMBL
    A0A7F8QN78
    Conserved Domains (4) summary
    cd16190
    Location:378 → 546
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:1 → 140
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:161 → 304
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:308 → 378
    Calpain_u2; Unstructured region on Calpain-3

  2. XM_031026402.1 → XP_030882262.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A7F8QM27
    Conserved Domains (4) summary
    cd16190
    Location:422 → 590
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:1 → 188
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:209 → 348
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:352 → 422
    Calpain_u2; Unstructured region on Calpain-3

  3. XM_031026405.1 → XP_030882265.1  calpain-3 isoform X5

    UniProtKB/TrEMBL
    A0A7F8QM42
    Conserved Domains (3) summary
    cd16190
    Location:382 → 550
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:1 → 188
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:209 → 352
    Calpain_III; Calpain large subunit, domain III

  4. XM_031026403.1 → XP_030882263.1  calpain-3 isoform X3

    UniProtKB/TrEMBL
    A0A7F8QPU1
    Conserved Domains (4) summary
    cd16190
    Location:420 → 588
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:1 → 188
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:209 → 352
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:356 → 420
    Calpain_u2; Unstructured region on Calpain-3

  5. XM_031026404.1 → XP_030882264.1  calpain-3 isoform X4

    UniProtKB/TrEMBL
    A0A7F8QM30

  6. XM_031026401.1 → XP_030882261.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A7F8QN73
    Conserved Domains (4) summary
    cd16190
    Location:426 → 594
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:1 → 188
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:209 → 352
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:356 → 426
    Calpain_u2; Unstructured region on Calpain-3

  7. XM_031026407.1 → XP_030882267.1  calpain-3 isoform X7

    UniProtKB/TrEMBL
    A0A7F8QM31
    Conserved Domains (3) summary
    cd16190
    Location:141 → 309
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam01067
    Location:1 → 67
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:71 → 141
    Calpain_u2; Unstructured region on Calpain-3
Nucleotide Protein
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