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LINC01291 long intergenic non-protein coding RNA 1291 [ Homo sapiens (human) ]

Gene ID: 102724515, updated on 30-Nov-2023

Summary

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Official Symbol
LINC01291provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1291provided by HGNC
Primary source
HGNC:HGNC:50358
See related
Ensembl:ENSG00000204792 AllianceGenome:HGNC:50358
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LINC01293
Expression
Low expression observed in reference dataset See more
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Genomic context

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See LINC01291 in Genome Data Viewer
Location:
2p12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (74909131..74938418)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (74918005..74947290)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (75136258..75165545)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11673 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11674 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:75061972-75062848 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:75064008-75064523 Neighboring gene Sharpr-MPRA regulatory region 11570 Neighboring gene HK2 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16083 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:75082772-75083312 Neighboring gene hexokinase 2 Neighboring gene uncharacterized LOC105374809 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:75185356-75185856 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:75185857-75186357 Neighboring gene DNA polymerase epsilon 4, accessory subunit Neighboring gene NANOG hESC enhancer GRCh37_chr2:75211079-75211580 Neighboring gene uncharacterized LOC124907850

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LINC01291 promotes hepatocellular carcinoma development by targeting the miR-186-5p/OXSR1 axis. Chu J, et al. J Gene Med, 2022 Feb. PMID 34665488
  2. Long noncoding RNA LINC01291 promotes the aggressive properties of melanoma by functioning as a competing endogenous RNA for microRNA-625-5p and subsequently increasing IGF-1R expression. Wu L, et al. Cancer Gene Ther, 2022 Mar. PMID 33674778, Free PMC Article
  3. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Dias Neto E, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10737800, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LINC01291 promotes hepatocellular carcinoma development by targeting the miR-186-5p/OXSR1 axis.
    Title: LINC01291 promotes hepatocellular carcinoma development by targeting the miR-186-5p/OXSR1 axis.
  2. Long noncoding RNA LINC01291 promotes the aggressive properties of melanoma by functioning as a competing endogenous RNA for microRNA-625-5p and subsequently increasing IGF-1R expression.
    Title: Long noncoding RNA LINC01291 promotes the aggressive properties of melanoma by functioning as a competing endogenous RNA for microRNA-625-5p and subsequently increasing IGF-1R expression.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • TCONS_00002938
  • long intergenic non-protein coding RNA 1293

Clone Names

  • FLJ43972, AC104135.3, AC104135.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_125792.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC104135
    Related
    ENST00000418204.1

  2. NR_189601.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC104135

  3. NR_189602.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC104135

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    74909131..74938418
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    74918005..74947290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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