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CT45A10 cancer/testis antigen family 45 member A10 [ Homo sapiens (human) ]

Gene ID: 102723631, updated on 3-Apr-2024

Summary

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Official Symbol
CT45A10provided by HGNC
Official Full Name
cancer/testis antigen family 45 member A10provided by HGNC
Primary source
HGNC:HGNC:51263
See related
Ensembl:ENSG00000269586 AllianceGenome:HGNC:51263
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT45-5; CT45A5
Summary
Enables identical protein binding activity. Predicted to be involved in snRNA 3'-end processing. Predicted to be part of integrator complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 7.2) See more
Orthologs
all
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Genomic context

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See CT45A10 in Genome Data Viewer
Location:
Xq26.3
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (135881065..135893444, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (134189395..134201774, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (134963215..134975595, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene cancer/testis antigen family 45 member A8 Neighboring gene cancer/testis antigen family 45 member A9 Neighboring gene Sharpr-MPRA regulatory region 13624 Neighboring gene sarcoma antigen 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:134987035-134988234 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:135014477-135014713 Neighboring gene cancer/testis antigen family 45 member A11, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Identification of cancer/testis-antigen genes by massively parallel signature sequencing. Chen YT, et al. Proc Natl Acad Sci U S A, 2005 May 31. PMID 15905330, Free PMC Article
  2. GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer. Shin EM, et al. Sci Adv, 2021 Mar. PMID 33731348, Free PMC Article
  3. The DNA sequence of the human X chromosome. Ross MT, et al. Nature, 2005 Mar 17. PMID 15772651, Free PMC Article
  4. A reference map of the human binary protein interactome. Luck K, et al. Nature, 2020 Apr. PMID 32296183, Free PMC Article
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • FLJ78398, MGC88118, MGC177967, MGC177968, MGC178071, MGC178072

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
cancer/testis antigen family 45 member A10
Names
Cancer/testis antigen 45-5
Cancer/testis antigen 45A10
Cancer/testis antigen 45A5
Cancer/testis antigen family 45 member A5
cancer/testis antigen family 45 member A-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291527.2 → NP_001278456.1  cancer/testis antigen family 45 member A10

    See identical proteins and their annotated locations for NP_001278456.1

    Status: VALIDATED

    Source sequence(s)
    AC240441
    Consensus CDS
    CCDS76035.1
    UniProtKB/Swiss-Prot
    P0DMU9
    Conserved Domains (1) summary
    pfam15300
    Location:122 → 183
    INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

  2. NM_001291528.2 → NP_001278457.1  cancer/testis antigen family 45 member A10

    See identical proteins and their annotated locations for NP_001278457.1

    Status: VALIDATED

    Source sequence(s)
    AC240441
    Consensus CDS
    CCDS76035.1
    UniProtKB/Swiss-Prot
    P0DMU9
    Related
    ENSP00000484601.1, ENST00000611668.4
    Conserved Domains (1) summary
    pfam15300
    Location:122 → 183
    INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

  3. NM_001291529.2 → NP_001278458.1  cancer/testis antigen family 45 member A10

    See identical proteins and their annotated locations for NP_001278458.1

    Status: VALIDATED

    Source sequence(s)
    AC240441
    Consensus CDS
    CCDS76035.1
    UniProtKB/Swiss-Prot
    P0DMU9
    Related
    ENSP00000507965.1, ENST00000682849.1
    Conserved Domains (1) summary
    pfam15300
    Location:122 → 183
    INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

  4. NM_001291530.2 → NP_001278459.1  cancer/testis antigen family 45 member A10

    See identical proteins and their annotated locations for NP_001278459.1

    Status: VALIDATED

    Source sequence(s)
    AC240441
    Consensus CDS
    CCDS76035.1
    UniProtKB/Swiss-Prot
    P0DMU9
    Conserved Domains (1) summary
    pfam15300
    Location:122 → 183
    INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

  5. NM_001385219.1 → NP_001372148.1  cancer/testis antigen family 45 member A10

    Status: VALIDATED

    Source sequence(s)
    AC240441
    Consensus CDS
    CCDS76035.1
    UniProtKB/Swiss-Prot
    P0DMU9
    Conserved Domains (1) summary
    pfam15300
    Location:122 → 183
    INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

  6. NM_001385220.1 → NP_001372149.1  cancer/testis antigen family 45 member A10

    Status: VALIDATED

    Source sequence(s)
    AC240441
    Consensus CDS
    CCDS76035.1
    UniProtKB/Swiss-Prot
    P0DMU9
    Conserved Domains (1) summary
    pfam15300
    Location:122 → 183
    INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    135881065..135893444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    134189395..134201774 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0DMU9.1 GenPept UniProtKB/Swiss-Prot:P0DMU9

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