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LOC102723553 small integral membrane protein 11B [ Homo sapiens (human) ]

Gene ID: 102723553, updated on 10-Oct-2023

Summary

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Gene symbol
LOC102723553
Gene description
small integral membrane protein 11B
See related
Ensembl:ENSG00000273590
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SMIM11B
Annotation information
Note: GeneID:102723553 is on a scaffold that is thought to be a false duplication and thus this gene is likely redundant with GeneID:54065. [11 Jun 2021]
Expression
Ubiquitous expression in brain (RPKM 3.4), thyroid (RPKM 3.2) and 25 other tissues See more
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Genomic context

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See LOC102723553 in Genome Data Viewer
Location:
21p11.2
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (7744951..7772245)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene CTBP2 pseudogene 9 Neighboring gene uncharacterized LOC102723360 Neighboring gene family with sequence similarity 243 member B Neighboring gene salivary glue protein Sgs-3-like Neighboring gene small integral membrane protein 34B Neighboring gene potassium voltage-gated channel subfamily E regulatory subunit 1B Neighboring gene small nucleolar RNA SNORA11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000021.9 Chromosome 21 Reference GRCh38.p14 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Dias Neto E, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10737800, Free PMC Article
  2. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. Suzuki Y, et al. Genome Res, 2004 Sep. PMID 15342556, Free PMC Article
  3. A reference map of the human binary protein interactome. Luck K, et al. Nature, 2020 Apr. PMID 32296183, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

General protein information

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Preferred Names
uncharacterized protein LOC102723553

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001313692.1 → NP_001300621.1  uncharacterized protein LOC102723553 isoform b

    Status: VALIDATED

    Source sequence(s)
    AW901268, BP194116, CU633980, DB526804
    UniProtKB/Swiss-Prot
    P58511
    Related
    ENST00000619874.5
    Conserved Domains (1) summary
    pfam14981
    Location:4 → 53
    FAM165; FAM165 family

  2. NM_001394150.1 → NP_001381079.1  uncharacterized protein LOC102723553 isoform a

    Status: VALIDATED

    Source sequence(s)
    CU633980
    UniProtKB/TrEMBL
    A0A8C8KJI4

  3. NM_001394151.1 → NP_001381080.1  uncharacterized protein LOC102723553 isoform a

    Status: VALIDATED

    Source sequence(s)
    CU633980
    UniProtKB/TrEMBL
    A0A8C8KJI4

  4. NM_001394152.1 → NP_001381081.1  uncharacterized protein LOC102723553 isoform b

    Status: VALIDATED

    Source sequence(s)
    CU633980
    UniProtKB/Swiss-Prot
    P58511
    Conserved Domains (1) summary
    pfam14981
    Location:4 → 53
    FAM165; FAM165 family

  5. NM_001394153.1 → NP_001381082.1  uncharacterized protein LOC102723553 isoform b

    Status: VALIDATED

    Source sequence(s)
    CU633980
    UniProtKB/Swiss-Prot
    P58511
    Conserved Domains (1) summary
    pfam14981
    Location:4 → 53
    FAM165; FAM165 family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    7744951..7772245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047440641.1 → XP_047296597.1  uncharacterized protein LOC102723553 isoform X1

    UniProtKB/Swiss-Prot
    P58511

  2. XM_017028205.2 → XP_016883694.1  uncharacterized protein LOC102723553 isoform X1

    UniProtKB/Swiss-Prot
    P58511
    Conserved Domains (1) summary
    pfam14981
    Location:4 → 53
    FAM165; FAM165 family

RNA

  1. XR_007067774.1 RNA Sequence

  2. XR_007067775.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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