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Phldb1 pleckstrin homology like domain, family B, member 1 [ Mus musculus (house mouse) ]

Gene ID: 102693, updated on 2-Nov-2024

Summary

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Official Symbol
Phldb1provided by MGI
Official Full Name
pleckstrin homology like domain, family B, member 1provided by MGI
Primary source
MGI:MGI:2143230
See related
Ensembl:ENSMUSG00000048537 AllianceGenome:MGI:2143230
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ll5a; Ll5alpha; D330037A14Rik
Summary
Predicted to be involved in regulation of embryonic development; regulation of epithelial to mesenchymal transition; and regulation of microtubule cytoskeleton organization. Predicted to be located in several cellular components, including cytosol; intercellular bridge; and plasma membrane. Predicted to be active in basal cortex. Human ortholog(s) of this gene implicated in osteogenesis imperfecta. Orthologous to human PHLDB1 (pleckstrin homology like domain family B member 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in mammary gland adult (RPKM 25.4), subcutaneous fat pad adult (RPKM 24.4) and 23 other tissues See more
Orthologs
human all
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Genomic context

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See Phldb1 in Genome Data Viewer
Location:
9 A5.2; 9 24.84 cM
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (44597605..44649800, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (44686308..44735248, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene cDNA sequence BC049987 Neighboring gene trehalase (brush-border membrane glycoprotein) Neighboring gene predicted gene, 24166 Neighboring gene archain 1 Neighboring gene STARR-positive B cell enhancer ABC_E9756 Neighboring gene intraflagellar transport 46

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification and characterization of human LL5A gene and mouse Ll5a gene in silico. Katoh M, et al. Int J Oncol, 2003 Nov. PMID 14532993
  2. A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes. Zhou QL, et al. J Biol Chem, 2010 Sep 3. PMID 20587420, Free PMC Article
  3. Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. Kerns RT, et al. J Neurosci, 2005 Mar 2. PMID 15745951, Free PMC Article
  4. A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain. García-Frigola C, et al. Brain Res Mol Brain Res, 2004 Mar 30. PMID 15010206
  5. Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice. Lenihan JA, et al. Mol Neurobiol, 2017 Dec. PMID 27889896

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PHLDB1 is a novel modulator of Akt protein kinase activation by insulin.
    Title: A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC32394

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in positive regulation of basement membrane assembly involved in embryonic body morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of epithelial to mesenchymal transition ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of gastrulation ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of microtubule cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in basal cortex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in basal cortex ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in intercellular bridge ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
pleckstrin homology-like domain family B member 1
Names
protein LL5-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001413419.1 → NP_001400348.1  pleckstrin homology-like domain family B member 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971

  2. NM_001413420.1 → NP_001400349.1  pleckstrin homology-like domain family B member 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971
    Related
    ENSMUSP00000120208.2, ENSMUST00000138356.8

  3. NM_001413421.1 → NP_001400350.1  pleckstrin homology-like domain family B member 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971

  4. NM_001413422.1 → NP_001400351.1  pleckstrin homology-like domain family B member 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC151971

  5. NM_001413423.1 → NP_001400352.1  pleckstrin homology-like domain family B member 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971

  6. NM_001413424.1 → NP_001400353.1  pleckstrin homology-like domain family B member 1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC151971

  7. NM_001413425.1 → NP_001400354.1  pleckstrin homology-like domain family B member 1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC151971

  8. NM_001413426.1 → NP_001400355.1  pleckstrin homology-like domain family B member 1 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC151971

  9. NM_001413427.1 → NP_001400356.1  pleckstrin homology-like domain family B member 1 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971

  10. NM_001413428.1 → NP_001400357.1  pleckstrin homology-like domain family B member 1 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC151971

  11. NM_001413429.1 → NP_001400358.1  pleckstrin homology-like domain family B member 1 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC151971

  12. NM_001413430.1 → NP_001400359.1  pleckstrin homology-like domain family B member 1 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC151971

  13. NM_001413431.1 → NP_001400360.1  pleckstrin homology-like domain family B member 1 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971

  14. NM_001413432.1 → NP_001400361.1  pleckstrin homology-like domain family B member 1 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC151971

  15. NM_001413433.1 → NP_001400362.1  pleckstrin homology-like domain family B member 1 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971

  16. NM_001413434.1 → NP_001400363.1  pleckstrin homology-like domain family B member 1 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC151971

  17. NM_001413435.1 → NP_001400364.1  pleckstrin homology-like domain family B member 1 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC151971

  18. NM_001413436.1 → NP_001400365.1  pleckstrin homology-like domain family B member 1 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971
    UniProtKB/TrEMBL
    E9PWB1
    Related
    ENSMUSP00000117395.2, ENSMUST00000134465.8

  19. NM_001413437.1 → NP_001400366.1  pleckstrin homology-like domain family B member 1 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AC151971

  20. NM_001413438.1 → NP_001400367.1  pleckstrin homology-like domain family B member 1 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AC151971

  21. NM_001413439.1 → NP_001400368.1  pleckstrin homology-like domain family B member 1 isoform 20

    Status: VALIDATED

    Source sequence(s)
    AC151971

  22. NM_001413440.1 → NP_001400369.1  pleckstrin homology-like domain family B member 1 isoform 20

    Status: VALIDATED

    Source sequence(s)
    AC151971

  23. NM_001413441.1 → NP_001400370.1  pleckstrin homology-like domain family B member 1 isoform 21

    Status: VALIDATED

    Source sequence(s)
    AC151971

  24. NM_001413442.1 → NP_001400371.1  pleckstrin homology-like domain family B member 1 isoform 21

    Status: VALIDATED

    Source sequence(s)
    AC151971

  25. NM_001413443.1 → NP_001400372.1  pleckstrin homology-like domain family B member 1 isoform 22

    Status: VALIDATED

    Source sequence(s)
    AC151971

  26. NM_001413444.1 → NP_001400373.1  pleckstrin homology-like domain family B member 1 isoform 23

    Status: VALIDATED

    Source sequence(s)
    AC151971

  27. NM_001413445.1 → NP_001400374.1  pleckstrin homology-like domain family B member 1 isoform 24

    Status: VALIDATED

    Source sequence(s)
    AC151971

  28. NM_001413446.1 → NP_001400375.1  pleckstrin homology-like domain family B member 1 isoform 25

    Status: VALIDATED

    Source sequence(s)
    AC151971

  29. NM_001413447.1 → NP_001400376.1  pleckstrin homology-like domain family B member 1 isoform 26

    Status: VALIDATED

    Source sequence(s)
    AC151971

  30. NM_001413448.1 → NP_001400377.1  pleckstrin homology-like domain family B member 1 isoform 27

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971

  31. NM_001413449.1 → NP_001400378.1  pleckstrin homology-like domain family B member 1 isoform 28

    Status: VALIDATED

    Source sequence(s)
    AC151971
    Related
    ENSMUSP00000121809.2, ENSMUST00000148344.8

  32. NM_001413450.1 → NP_001400379.1  pleckstrin homology-like domain family B member 1 isoform 28

    Status: VALIDATED

    Source sequence(s)
    AC151971

  33. NM_001413451.1 → NP_001400380.1  pleckstrin homology-like domain family B member 1 isoform 30

    Status: VALIDATED

    Source sequence(s)
    AC151971

  34. NM_001413452.1 → NP_001400381.1  pleckstrin homology-like domain family B member 1 isoform 31

    Status: VALIDATED

    Source sequence(s)
    AC151971

  35. NM_001413453.1 → NP_001400382.1  pleckstrin homology-like domain family B member 1 isoform 32

    Status: VALIDATED

    Source sequence(s)
    AC151971

  36. NM_001413454.1 → NP_001400383.1  pleckstrin homology-like domain family B member 1 isoform 33

    Status: VALIDATED

    Source sequence(s)
    AC151971

  37. NM_001413455.1 → NP_001400384.1  pleckstrin homology-like domain family B member 1 isoform 34

    Status: VALIDATED

    Source sequence(s)
    AC151971

  38. NM_001413456.1 → NP_001400385.1  pleckstrin homology-like domain family B member 1 isoform 35

    Status: VALIDATED

    Source sequence(s)
    AC151971

  39. NM_001413457.1 → NP_001400386.1  pleckstrin homology-like domain family B member 1 isoform 36

    Status: VALIDATED

    Source sequence(s)
    AC151971
    UniProtKB/TrEMBL
    E9PWW4
    Related
    ENSMUSP00000114773.2, ENSMUST00000144251.8

  40. NM_153537.5 → NP_705765.3  pleckstrin homology-like domain family B member 1 isoform 6

    See identical proteins and their annotated locations for NP_705765.3

    Status: VALIDATED

    Source sequence(s)
    AC142113, AC151971
    Consensus CDS
    CCDS23118.1
    UniProtKB/Swiss-Prot
    Q6PDH0, Q80TV2
    UniProtKB/TrEMBL
    D3Z4N0
    Related
    ENSMUSP00000034611.9, ENSMUST00000034611.15
    Conserved Domains (7) summary
    cd14673
    Location:1260 → 1364
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:1263 → 1359
    PH; PH domain
    pfam00498
    Location:64 → 124
    FHA; FHA domain
    pfam14988
    Location:731 → 936
    DUF4515; Domain of unknown function (DUF4515)
    cd16269
    Location:778 → 791
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:717 → 902
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl20817
    Location:719 → 806
    GBP_C; Guanylate-binding protein, C-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    44597605..44649800 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154520.1 → XP_036010413.1  pleckstrin homology-like domain family B member 1 isoform X28

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1311 → 1426
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1001
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  2. XM_030243976.2 → XP_030099836.2  pleckstrin homology-like domain family B member 1 isoform X26

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1322 → 1437
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1001
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  3. XM_030243975.2 → XP_030099835.2  pleckstrin homology-like domain family B member 1 isoform X24

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1337 → 1452
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1001
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  4. XM_030243974.2 → XP_030099834.2  pleckstrin homology-like domain family B member 1 isoform X20

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1358 → 1473
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1039
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  5. XM_036154514.1 → XP_036010407.1  pleckstrin homology-like domain family B member 1 isoform X19

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1369 → 1473
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1039
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  6. XM_030243971.2 → XP_030099831.2  pleckstrin homology-like domain family B member 1 isoform X16

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1384 → 1499
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1039
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  7. XM_036154511.1 → XP_036010404.1  pleckstrin homology-like domain family B member 1 isoform X11

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1425 → 1529
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1001
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  8. XM_030243968.2 → XP_030099828.2  pleckstrin homology-like domain family B member 1 isoform X9

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1425 → 1540
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1001
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  9. XM_036154510.1 → XP_036010403.1  pleckstrin homology-like domain family B member 1 isoform X10

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1429 → 1533
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1001
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  10. XM_030243966.2 → XP_030099826.2  pleckstrin homology-like domain family B member 1 isoform X7

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1440 → 1555
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1001
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  11. XM_036154517.1 → XP_036010410.1  pleckstrin homology-like domain family B member 1 isoform X23

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (5) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1354 → 1458
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:787 → 1335
    SMC_N; RecF/RecN/SMC N terminal domain
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  12. XM_030243973.2 → XP_030099833.2  pleckstrin homology-like domain family B member 1 isoform X18

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (5) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1365 → 1480
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:787 → 1350
    SMC_N; RecF/RecN/SMC N terminal domain
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  13. XM_036154515.1 → XP_036010408.1  pleckstrin homology-like domain family B member 1 isoform X21

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (5) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1369 → 1473
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:787 → 1350
    SMC_N; RecF/RecN/SMC N terminal domain
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  14. XM_030243972.2 → XP_030099832.2  pleckstrin homology-like domain family B member 1 isoform X17

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1380 → 1495
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  15. XM_036154513.1 → XP_036010406.1  pleckstrin homology-like domain family B member 1 isoform X14

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (5) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1401 → 1516
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:787 → 1382
    SMC_N; RecF/RecN/SMC N terminal domain
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  16. XM_030243969.2 → XP_030099829.2  pleckstrin homology-like domain family B member 1 isoform X12

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (5) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1412 → 1527
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:787 → 1397
    SMC_N; RecF/RecN/SMC N terminal domain
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  17. XM_030243967.2 → XP_030099827.2  pleckstrin homology-like domain family B member 1 isoform X8

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (5) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1427 → 1542
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:787 → 1412
    SMC_N; RecF/RecN/SMC N terminal domain
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  18. XM_030243965.2 → XP_030099825.2  pleckstrin homology-like domain family B member 1 isoform X6

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1457 → 1572
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  19. XM_030243964.2 → XP_030099824.2  pleckstrin homology-like domain family B member 1 isoform X5

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1472 → 1576
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  20. XM_030243962.2 → XP_030099822.2  pleckstrin homology-like domain family B member 1 isoform X4

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1483 → 1598
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  21. XM_030243956.2 → XP_030099816.2  pleckstrin homology-like domain family B member 1 isoform X3

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1520 → 1624
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  22. XM_030243954.2 → XP_030099814.2  pleckstrin homology-like domain family B member 1 isoform X2

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1520 → 1635
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  23. XM_030243953.2 → XP_030099813.2  pleckstrin homology-like domain family B member 1 isoform X1

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:251 → 646
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1531 → 1635
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:743 → 1034
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00498
    Location:162 → 222
    FHA; FHA domain

  24. XM_030243980.2 → XP_030099840.1  pleckstrin homology-like domain family B member 1 isoform X38

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (4) summary
    PHA03307
    Location:33 → 428
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:563 → 816
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd14673
    Location:1183 → 1298
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam02463
    Location:548 → 1164
    SMC_N; RecF/RecN/SMC N terminal domain

  25. XM_036154529.1 → XP_036010422.1  pleckstrin homology-like domain family B member 1 isoform X36

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (4) summary
    PHA03307
    Location:33 → 428
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1194 → 1309
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:525 → 816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:569 → 1179
    SMC_N; RecF/RecN/SMC N terminal domain

  26. XM_030243979.2 → XP_030099839.1  pleckstrin homology-like domain family B member 1 isoform X30

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (3) summary
    PHA03307
    Location:33 → 428
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1265 → 1380
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:566 → 825
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  27. XM_036154537.1 → XP_036010430.1  pleckstrin homology-like domain family B member 1 isoform X45

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (3) summary
    PHA03307
    Location:33 → 428
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1104 → 1219
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:525 → 783
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  28. XM_036154535.1 → XP_036010428.1  pleckstrin homology-like domain family B member 1 isoform X43

    UniProtKB/TrEMBL
    D3Z4N0
    Conserved Domains (3) summary
    PHA03307
    Location:33 → 428
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1119 → 1234
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:525 → 783
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  29. XM_030243981.1 → XP_030099841.1  pleckstrin homology-like domain family B member 1 isoform X40

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (3) summary
    PHA03307
    Location:33 → 428
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:595 → 783
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd14673
    Location:1166 → 1281
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain

  30. XM_036154523.1 → XP_036010416.1  pleckstrin homology-like domain family B member 1 isoform X33

    UniProtKB/TrEMBL
    D3Z0X5
    Conserved Domains (3) summary
    PHA03307
    Location:33 → 428
    PHA03307; transcriptional regulator ICP4; Provisional
    cd14673
    Location:1207 → 1322
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:525 → 783
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PDH0.1 GenPept UniProtKB/Swiss-Prot:Q6PDH0

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