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PLCG1 phospholipase C gamma 1 [ Alligator mississippiensis (American alligator) ]

Gene ID: 102563626, updated on 8-May-2024

Summary

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Gene symbol
PLCG1
Gene description
phospholipase C gamma 1
Locus tag
Y1Q_0002811
See related
EnsemblRapid:ENSAMIG00015006390
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator mississippiensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2023_09 current rAllMis1 (GCF_030867095.1) 9 NC_081832.1 (17731794..17812608, complement)
102 previous assembly ASM28112v4 (GCF_000281125.3) Unplaced Scaffold NW_017708899.1 (14077254..14158538, complement)

Chromosome 9 - NC_081832.1Genomic Context describing neighboring genes Neighboring gene elastin microfibril interfacer 3 Neighboring gene lipin 3 Neighboring gene zinc fingers and homeoboxes 3 Neighboring gene U4 spliceosomal RNA Neighboring gene DNA topoisomerase I Neighboring gene uncharacterized LOC132243374

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epithelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030867095.1-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rAllMis1 Primary Assembly

Genomic

  1. NC_081832.1 Reference rAllMis1 Primary Assembly

    Range
    17731794..17812608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014609711.3 → XP_014465197.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

    UniProtKB/TrEMBL
    A0A151P030
    Related
    ENSAMIP00015008071.1, ENSAMIT00015011555.1
    Conserved Domains (10) summary
    smart00149
    Location:945 → 1060
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1079 → 1202
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:311 → 457
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:654 → 756
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:536 → 640
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:782 → 841
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:855 → 924
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:24 → 146
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    pfam00169
    Location:61 → 137
    PH; PH domain
    cl17171
    Location:480 → 516
    PH-like; Pleckstrin homology-like domain

  2. XM_014609712.3 → XP_014465198.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2

    UniProtKB/TrEMBL
    A0A151NZG7
    Conserved Domains (10) summary
    smart00149
    Location:945 → 1060
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1079 → 1202
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:311 → 457
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:654 → 756
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:536 → 640
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:782 → 841
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:855 → 924
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:24 → 146
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    pfam00169
    Location:61 → 137
    PH; PH domain
    cl17171
    Location:480 → 516
    PH-like; Pleckstrin homology-like domain

  3. XM_006275842.4 → XP_006275904.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

    UniProtKB/TrEMBL
    A0A151P030
    Conserved Domains (10) summary
    smart00149
    Location:945 → 1060
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1079 → 1202
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:311 → 457
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:654 → 756
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:536 → 640
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:782 → 841
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:855 → 924
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:24 → 146
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    pfam00169
    Location:61 → 137
    PH; PH domain
    cl17171
    Location:480 → 516
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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