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PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [ Alligator mississippiensis (American alligator) ]

Gene ID: 102559272, updated on 8-May-2024

Summary

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Gene symbol
PIK3CG
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Locus tag
Y1Q_0023347
See related
EnsemblRapid:ENSAMIG00015021486
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator mississippiensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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See PIK3CG in Genome Data Viewer
Location:
chromosome: 4
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current rAllMis1 (GCF_030867095.1) 4 NC_081827.1 (27353869..27396626)
102 previous assembly ASM28112v4 (GCF_000281125.3) Unplaced Scaffold NW_017709854.1 (6589027..6620142, complement)

Chromosome 4 - NC_081827.1Genomic Context describing neighboring genes Neighboring gene nicotinamide phosphoribosyltransferase Neighboring gene coiled-coil domain containing 71 like Neighboring gene protein kinase cAMP-dependent type II regulatory subunit beta Neighboring gene HMG-box transcription factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IA IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IB IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030867095.1-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rAllMis1 Primary Assembly

Genomic

  1. NC_081827.1 Reference rAllMis1 Primary Assembly

    Range
    27353869..27396626
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059725869.1 → XP_059581852.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X2

  2. XM_019487455.2 → XP_019343000.2  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X3

  3. XM_059725868.1 → XP_059581851.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1

    Related
    ENSAMIP00015029548.1, ENSAMIT00015040726.1

  4. XM_006273990.4 → XP_006274052.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X2

    See identical proteins and their annotated locations for XP_006274052.1

    Related
    ENSAMIP00015029540.1, ENSAMIT00015040718.1
    Conserved Domains (4) summary
    cd08399
    Location:350 → 530
    C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:552 → 728
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd00894
    Location:732 → 1098
    PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
    cl02484
    Location:203 → 312
    PI3K_rbd; PI3-kinase family, ras-binding domain

RNA

  1. XR_009461517.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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