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Ankfn1 ankyrin-repeat and fibronectin type III domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 102551403, updated on 2-Nov-2024

Summary

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Symbol
Ankfn1provided by RGD
Full Name
ankyrin-repeat and fibronectin type III domain containing 1provided by RGD
Primary source
RGD:7736477
See related
EnsemblRapid:ENSRNOG00000081540 AllianceGenome:RGD:7736477
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ankfn1-ps1; Rgd1559713
Summary
Predicted to act upstream of or within behavioral fear response; equilibrioception; and locomotor rhythm. Orthologous to human ANKFN1 (ankyrin repeat and fibronectin type III domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 14.5), Brain (RPKM 10.8) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ankfn1 in Genome Data Viewer
Location:
10q26
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (74711284..75099954, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (74214143..74602825, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (76901681..77210042, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095173 Neighboring gene noggin like 1 Neighboring gene noggin Neighboring gene uncharacterized LOC134480856 Neighboring gene uncharacterized LOC120095174 Neighboring gene uncharacterized LOC103693415 Neighboring gene phosphatidylcholine transfer protein Neighboring gene transmembrane protein 100

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Nmf9 Encodes a Highly Conserved Protein Important to Neurological Function in Mice and Flies. Zhang S, et al. PLoS Genet, 2015 Jul. PMID 26131556, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within behavioral fear response ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within equilibrioception ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within locomotor rhythm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ankyrin repeat and fibronectin type-III domain-containing protein 1
Names
ankyrin repeat and fibronectin type-III domain-containing protein 1-like
ankyrin-repeat and fibronectin type III domain containing 1, pseudogene 1
rCG64351-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    74711284..75099954 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039087383.2 → XP_038943311.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZLK6, A0A8I6A9Z7
    Conserved Domains (3) summary
    cd00063
    Location:200 → 293
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:66 → 100
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:70 → 123
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_039087381.2 → XP_038943309.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZLK6, A0A8I6A9Z7
    Conserved Domains (3) summary
    cd00063
    Location:200 → 293
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:66 → 100
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:70 → 123
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_039087379.2 → XP_038943307.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZLK6
    Conserved Domains (4) summary
    COG0666
    Location:57 → 214
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:141 → 194
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_039087378.1 → XP_038943306.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZLK6
    Conserved Domains (4) summary
    COG0666
    Location:64 → 221
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:278 → 371
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:144 → 178
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:148 → 201
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_039087382.2 → XP_038943310.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZLK6, A0A8I6A9Z7
    Conserved Domains (3) summary
    cd00063
    Location:200 → 293
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:66 → 100
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:70 → 123
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_039087384.2 → XP_038943312.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I6GDF6
    Related
    ENSRNOP00000085867.3, ENSRNOT00000110340.3
    Conserved Domains (4) summary
    COG0666
    Location:64 → 221
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:278 → 371
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:144 → 178
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:148 → 201
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein Strain
Heading Accession and Version

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