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MCC MCC regulator of WNT signaling pathway [ Camelus ferus (Wild Bactrian camel) ]

Gene ID: 102524393, updated on 10-Mar-2024

Summary

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Gene symbol
MCC
Gene description
MCC regulator of WNT signaling pathway
Locus tag
CB1_001814009
See related
EnsemblRapid:ENSCFEG00005002207
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus ferus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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See MCC in Genome Data Viewer
Location:
chromosome: 3
Exon count:
22
Annotation release Status Assembly Chr Location
102 current BCGSAC_Cfer_1.0 (GCF_009834535.1) 3 NC_045698.1 (76489340..76861199)
101 previous assembly CB1 (GCF_000311805.1) Unplaced Scaffold NW_006211988.1 (858847..1228675, complement)

Chromosome 3 - NC_045698.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 36 Neighboring gene calcium/calmodulin dependent protein kinase IV Neighboring gene StAR related lipid transfer domain containing 4 Neighboring gene uncharacterized LOC116662656 Neighboring gene tumor protein D54-like Neighboring gene uncharacterized LOC116662657 Neighboring gene decapping mRNA 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequences of wild and domestic bactrian camels. Bactrian Camels Genome Sequencing and Analysis Consortium, et al. Nat Commun, 2012. PMID 23149746, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
colorectal mutant cancer protein
Names
MCC, WNT signaling pathway regulator
mutated in colorectal cancers

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Camelus ferus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCGSAC_Cfer_1.0 Primary Assembly

Genomic

  1. NC_045698.1 Reference BCGSAC_Cfer_1.0 Primary Assembly

    Range
    76489340..76861199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006192560.2 → XP_006192622.2  colorectal mutant cancer protein isoform X1

    UniProtKB/TrEMBL
    A0A8B6YMC1
    Related
    ENSCFEP00005003481.1, ENSCFET00005003968.1
    Conserved Domains (4) summary
    COG1196
    Location:747 → 1010
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:212 → 455
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam10506
    Location:591 → 655
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
    pfam13499
    Location:34 → 90
    EF-hand_7; EF-hand domain pair

  2. XM_032476494.1 → XP_032332385.1  colorectal mutant cancer protein isoform X3

    UniProtKB/TrEMBL
    A0A8B8SR56
    Related
    ENSCFEP00005003531.1, ENSCFET00005004019.1
    Conserved Domains (3) summary
    COG1196
    Location:558 → 821
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:15 → 266
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam10506
    Location:402 → 466
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome

  3. XM_032476495.1 → XP_032332386.1  colorectal mutant cancer protein isoform X4

    UniProtKB/TrEMBL
    A0A8B8SQE8
    Related
    ENSCFEP00005003588.1, ENSCFET00005004083.1
    Conserved Domains (3) summary
    COG1196
    Location:554 → 817
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:19 → 262
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam10506
    Location:398 → 462
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome

  4. XM_032476493.1 → XP_032332384.1  colorectal mutant cancer protein isoform X2

    UniProtKB/TrEMBL
    A0A8B8SRJ3
    Conserved Domains (2) summary
    COG1196
    Location:683 → 946
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10506
    Location:527 → 591
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
Nucleotide Protein
Heading Accession and Version

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