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PDE2A phosphodiesterase 2A [ Camelus ferus (Wild Bactrian camel) ]

Gene ID: 102508040, updated on 18-Sep-2024

Summary

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Gene symbol
PDE2A
Gene description
phosphodiesterase 2A
Locus tag
CB1_000558024
See related
EnsemblRapid:ENSCFEG00005002973
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus ferus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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See PDE2A in Genome Data Viewer
Location:
chromosome: 10
Exon count:
32
Annotation release Status Assembly Chr Location
102 current BCGSAC_Cfer_1.0 (GCF_009834535.1) 10 NC_045705.1 (57732496..57796049, complement)
101 previous assembly CB1 (GCF_000311805.1) Unplaced Scaffold NW_006210734.1 (1685891..1750660)

Chromosome 10 - NC_045705.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC116666469 Neighboring gene 40S ribosomal protein S12-like Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 Neighboring gene StAR related lipid transfer domain containing 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 3',5'-cyclic-GMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cAMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cGMP catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cGMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cAMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cGMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitochondrion organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cGMP-dependent 3',5'-cyclic phosphodiesterase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Camelus ferus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCGSAC_Cfer_1.0 Primary Assembly

Genomic

  1. NC_045705.1 Reference BCGSAC_Cfer_1.0 Primary Assembly

    Range
    57732496..57796049 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032489287.1 → XP_032345178.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    A0A8B8TTG1, S9Y7R2
    Related
    ENSCFEP00005004734.1, ENSCFET00005005412.1
    Conserved Domains (2) summary
    smart00065
    Location:403 → 552
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:649 → 882
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  2. XM_032489289.1 → XP_032345180.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X2

    UniProtKB/TrEMBL
    A0A8B8TT96, S9Y7R2
    Related
    ENSCFEP00005004676.1, ENSCFET00005005346.1
    Conserved Domains (2) summary
    smart00065
    Location:389 → 538
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:635 → 868
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  3. XM_032489290.1 → XP_032345181.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X3

    UniProtKB/TrEMBL
    A0A8B8TSC8, S9Y7R2
    Related
    ENSCFEP00005004905.1, ENSCFET00005005605.1
    Conserved Domains (2) summary
    smart00065
    Location:263 → 412
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:509 → 742
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
Nucleotide Protein
Heading Accession and Version

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