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ALOX12 arachidonate 12-lipoxygenase, 12S type [ Camelus ferus (Wild Bactrian camel) ]

Gene ID: 102504047, updated on 10-Mar-2024

Summary

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Gene symbol
ALOX12
Gene description
arachidonate 12-lipoxygenase, 12S type
Locus tag
CB1_000230001
See related
EnsemblRapid:ENSCFEG00005009064
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus ferus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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See ALOX12 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
14
Annotation release Status Assembly Chr Location
102 current BCGSAC_Cfer_1.0 (GCF_009834535.1) 16 NC_045711.1 (11586165..11597384)
101 previous assembly CB1 (GCF_000311805.1) Unplaced Scaffold NW_006210406.1 (49661..59196)

Chromosome 16 - NC_045711.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116669295 Neighboring gene uncharacterized LOC106728569 Neighboring gene uncharacterized LOC106728568 Neighboring gene ribonuclease K Neighboring gene BPTF associated chromatin complex component 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequences of wild and domestic bactrian camels. Bactrian Camels Genome Sequencing and Analysis Consortium, et al. Nat Commun, 2012. PMID 23149746, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables arachidonate 15-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables linoleate 13S-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 12-lipoxygenase, 12S-type

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Camelus ferus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCGSAC_Cfer_1.0 Primary Assembly

Genomic

  1. NC_045711.1 Reference BCGSAC_Cfer_1.0 Primary Assembly

    Range
    11586165..11597384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032498581.1 → XP_032354472.1  arachidonate 12-lipoxygenase, 12S-type

    UniProtKB/TrEMBL
    A0A8B8UJC0, T0MFK9
    Related
    ENSCFEP00005015201.1, ENSCFET00005016953.1
    Conserved Domains (2) summary
    cd01753
    Location:2 → 111
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:222 → 654
    Lipoxygenase
Nucleotide Protein
Heading Accession and Version

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