U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ARHGAP12 Rho GTPase activating protein 12 [ Tupaia chinensis (Chinese tree shrew) ]

Gene ID: 102484951, updated on 10-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
ARHGAP12
Gene description
Rho GTPase activating protein 12
Locus tag
TREES_T100007886
Gene type
protein coding
RefSeq status
MODEL
Organism
Tupaia chinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ARHGAP12 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
102 current TupChi_1.0 (GCF_000334495.1) Unplaced Scaffold NW_006160094.1 (1176783..1295852, complement)

NW_006160094.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene transcription initiation factor IIA subunit 2 pseudogene Neighboring gene destrin pseudogene Neighboring gene kinesin family member 5B Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_006160094 Unplaced Scaffold Reference TupChi_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus. Yan H, et al. Elife, 2012 Nov 13. PMID 23150796, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
rho GTPase-activating protein 12

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Tupaia chinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TupChi_1.0

Genomic

  1. NW_006160094.1 Reference TupChi_1.0

    Range
    1176783..1295852 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006158279.3 → XP_006158341.1  rho GTPase-activating protein 12 isoform X4

    UniProtKB/TrEMBL
    L9JDR0
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    cd00201
    Location:266 → 296
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:573 → 758
    RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
    cd13233
    Location:386 → 497
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00169
    Location:396 → 496
    PH; PH domain
    pfam16618
    Location:69 → 264
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  2. XM_006158278.3 → XP_006158340.1  rho GTPase-activating protein 12 isoform X3

    UniProtKB/TrEMBL
    L9JDR0
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    cd00201
    Location:266 → 296
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:598 → 783
    RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
    cd13233
    Location:411 → 522
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00169
    Location:421 → 521
    PH; PH domain
    pfam16618
    Location:69 → 264
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  3. XM_006158277.3 → XP_006158339.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    L9JDR0
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    cd00201
    Location:266 → 296
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:620 → 805
    RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
    cd13233
    Location:433 → 544
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00169
    Location:443 → 543
    PH; PH domain
    pfam16618
    Location:69 → 264
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  4. XM_006158276.3 → XP_006158338.1  rho GTPase-activating protein 12 isoform X1

    UniProtKB/TrEMBL
    L9JDR0
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    cd00201
    Location:266 → 296
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:645 → 830
    RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
    cd13233
    Location:458 → 569
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam00169
    Location:468 → 568
    PH; PH domain
    pfam16618
    Location:69 → 264
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.