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MIR6880 microRNA 6880 [ Homo sapiens (human) ]

Gene ID: 102466204, updated on 10-Oct-2023

Summary

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Official Symbol
MIR6880provided by HGNC
Official Full Name
microRNA 6880provided by HGNC
Primary source
HGNC:HGNC:50187
See related
Ensembl:ENSG00000275967 miRBase:MI0022727; AllianceGenome:HGNC:50187
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
hsa-mir-6880
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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Location:
12q24.31
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (124337181..124337242, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (124339755..124339816, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (124821727..124821788, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124456863-124457600 Neighboring gene ZNF664-RFLNA readthrough Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5053 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5054 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5055 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7276 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5056 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7277 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7278 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7279 Neighboring gene zinc finger protein 664 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:124556312-124557118 Neighboring gene NANOG hESC enhancer GRCh37_chr12:124594949-124595450 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124600014-124600560 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124601106-124601651 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124601652-124602196 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:124608857-124609358 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:124624781-124625523 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124625524-124626265 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr12:124630091-124630857 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124666563-124667068 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124673184-124673704 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124672664-124673183 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124672143-124672663 Neighboring gene Sharpr-MPRA regulatory region 13038 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124725860-124726762 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7280 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124786919-124787420 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124801665-124802264 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7281 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7282 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7283 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:124821000-124821180 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124828658-124829158 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124829159-124829659 Neighboring gene refilin A Neighboring gene Sharpr-MPRA regulatory region 3491 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124853631-124854132 Neighboring gene nuclear receptor corepressor 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124866136-124866684 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124866685-124867231 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124868677-124869413 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124870150-124870886 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124869414-124870149 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124870887-124871621 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5057 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7284 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124876499-124877188 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124879259-124879948 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124879949-124880636 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124883733-124884232 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124887188-124887832 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124887833-124888476 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124896741-124897368 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124897369-124897997 Neighboring gene Sharpr-MPRA regulatory region 11802 Neighboring gene uncharacterized LOC124903044 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124911835-124912374 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124912375-124912913 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124917115-124917722 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124917723-124918330 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7285 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124924007-124924726 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124924727-124925447 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124937508-124938346 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5058 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5059 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124947144-124947710 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124947711-124948278 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7287 Neighboring gene conserved acetylation island sequence 32 enhancer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5060 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124963398-124963907 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124964417-124964926 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124964927-124965434 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7289 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7288 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124975405-124975905 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124979536-124980495 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:124980496-124981454 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr12:124988989-124990188 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124992013-124992598 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:124992911-124993125 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124993187-124993772 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124996849-124997397 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:124997398-124997946 Neighboring gene uncharacterized LOC105370047

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. Ladewig E, et al. Genome Res, 2012 Sep. PMID 22955976, Free PMC Article
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • microRNA mir-6880

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_106940.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC073916
    Related
    ENST00000622851.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    124337181..124337242 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    124339755..124339816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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