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PKD2 polycystin 2, transient receptor potential cation channel [ Pelodiscus sinensis (Chinese soft-shelled turtle) ]

Gene ID: 102448832, updated on 10-Mar-2024

Summary

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Gene symbol
PKD2
Gene description
polycystin 2, transient receptor potential cation channel
See related
Ensembl:ENSPSIG00000002360
Gene type
protein coding
RefSeq status
MODEL
Organism
Pelodiscus sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia; Trionychidae; Pelodiscus
Orthologs
human mouse all
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Genomic context

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See PKD2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current PelSin_1.0 (GCF_000230535.1) Unplaced Scaffold NW_005857322.1 (153448..204402, complement)

NW_005857322.1Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette sub-family G member 2-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005857322 Unplaced Scaffold Reference PelSin_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables muscle alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of mechanical stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
polycystin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pelodiscus sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PelSin_1.0 Primary Assembly

Genomic

  1. NW_005857322.1 Reference PelSin_1.0 Primary Assembly

    Range
    153448..204402 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006130870.3 → XP_006130932.2  polycystin-2

    UniProtKB/TrEMBL
    K7F2Y5, K7F2Y6
    Related
    ENSPSIP00000002396.1, ENSPSIT00000002404.1
    Conserved Domains (2) summary
    pfam08016
    Location:106 → 527
    PKD_channel; Polycystin cation channel
    cl08302
    Location:572 → 618
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
Heading Accession and Version

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