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PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [ Pelodiscus sinensis (Chinese soft-shelled turtle) ]

Gene ID: 102448624, updated on 10-Mar-2024

Summary

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Gene symbol
PIK3CA
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
See related
Ensembl:ENSPSIG00000014440
Gene type
protein coding
RefSeq status
MODEL
Organism
Pelodiscus sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia; Trionychidae; Pelodiscus
Orthologs
human mouse all
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Genomic context

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See PIK3CA in Genome Data Viewer
Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
102 current PelSin_1.0 (GCF_000230535.1) Unplaced Scaffold NW_005871022.1 (5606706..5658372, complement)

NW_005871022.1Genomic Context describing neighboring genes Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC112543928 Neighboring gene zinc finger matrin-type 3 Neighboring gene potassium calcium-activated channel subfamily M regulatory beta subunit 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005871022 Unplaced Scaffold Reference PelSin_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IA IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IB IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pelodiscus sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PelSin_1.0 Primary Assembly

Genomic

  1. NW_005871022.1 Reference PelSin_1.0 Primary Assembly

    Range
    5606706..5658372 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006139707.3 → XP_006139769.1  LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

    UniProtKB/TrEMBL
    K7G7C8
    Related
    ENSPSIP00000016189.1, ENSPSIT00000016265.1
    Conserved Domains (5) summary
    cd08398
    Location:325 → 484
    C2_PI3K_class_I_alpha; C2 domain present in class I alpha phosphatidylinositol 3-kinases (PI3Ks)
    smart00144
    Location:173 → 292
    PI3K_rbd; PI3-kinase family, Ras-binding domain
    cd00872
    Location:525 → 696
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl21453
    Location:695 → 1058
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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