U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PSEN1 presenilin 1 [ Myotis lucifugus (little brown bat) ]

Gene ID: 102435757, updated on 30-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
PSEN1
Gene description
presenilin 1
See related
Ensembl:ENSMLUG00000015451
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis lucifugus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PSEN1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current Myoluc2.0 (GCF_000147115.1) Unplaced Scaffold NW_005871255.1 (1515973..1585760)

NW_005871255.1Genomic Context describing neighboring genes Neighboring gene zinc finger FYVE-type containing 1 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene RNA binding motif protein 25 Neighboring gene papilin, proteoglycan like sulfated glycoprotein Neighboring gene NUMB endocytic adaptor protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_005871255 Unplaced Scaffold Reference Myoluc2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in amyloid precursor protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in calcium ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smooth endoplasmic reticulum calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ciliary rootlet IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic shaft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
presenilin-1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Myotis lucifugus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Myoluc2.0

Genomic

  1. NW_005871255.1 Reference Myoluc2.0

    Range
    1515973..1585760
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006097603.3 → XP_006097665.2  presenilin-1 isoform X1

    Conserved Domains (1) summary
    pfam01080
    Location:109 → 490
    Presenilin; Presenilin

  2. XM_006097601.3 → XP_006097663.2  presenilin-1 isoform X1

    Conserved Domains (1) summary
    pfam01080
    Location:109 → 490
    Presenilin; Presenilin

  3. XM_014463346.2 → XP_014318832.1  presenilin-1 isoform X1

    Conserved Domains (1) summary
    pfam01080
    Location:109 → 490
    Presenilin; Presenilin

  4. XM_023761320.1 → XP_023617088.1  presenilin-1 isoform X2

    Conserved Domains (1) summary
    pfam01080
    Location:108 → 489
    Presenilin

  5. XM_006097602.3 → XP_006097664.1  presenilin-1 isoform X7

    See identical proteins and their annotated locations for XP_006097664.1

    UniProtKB/TrEMBL
    G1PSD4
    Related
    ENSMLUP00000014078.2, ENSMLUT00000015449.2
    Conserved Domains (1) summary
    pfam01080
    Location:77 → 458
    Presenilin; Presenilin

  6. XM_014463348.2 → XP_014318834.1  presenilin-1 isoform X3

    Conserved Domains (1) summary
    pfam01080
    Location:105 → 486
    Presenilin; Presenilin

  7. XM_023761322.1 → XP_023617090.1  presenilin-1 isoform X4

    Conserved Domains (1) summary
    pfam01080
    Location:104 → 485
    Presenilin

  8. XM_014463349.2 → XP_014318835.1  presenilin-1 isoform X8

    Conserved Domains (1) summary
    pfam01080
    Location:73 → 454
    Presenilin; Presenilin

  9. XM_014463347.2 → XP_014318833.1  presenilin-1 isoform X1

    Conserved Domains (1) summary
    pfam01080
    Location:109 → 490
    Presenilin; Presenilin

  10. XM_006097600.3 → XP_006097662.1  presenilin-1 isoform X5

    Conserved Domains (1) summary
    pfam01080
    Location:84 → 465
    Presenilin; Presenilin

  11. XM_023761323.1 → XP_023617091.1  presenilin-1 isoform X6

    Conserved Domains (1) summary
    pfam01080
    Location:83 → 464
    Presenilin

  12. XM_023761324.1 → XP_023617092.1  presenilin-1 isoform X9

    Conserved Domains (1) summary
    pfam01080
    Location:52 → 433
    Presenilin

  13. XM_023761325.1 → XP_023617093.1  presenilin-1 isoform X10

    Conserved Domains (1) summary
    pfam01080
    Location:1 → 374
    Presenilin
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.