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HES1 hes family bHLH transcription factor 1 [ Myotis lucifugus (little brown bat) ]

Gene ID: 102417036, updated on 30-Mar-2024

Summary

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Gene symbol
HES1
Gene description
hes family bHLH transcription factor 1
See related
Ensembl:ENSMLUG00000008549
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis lucifugus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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See HES1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
102 current Myoluc2.0 (GCF_000147115.1) Unplaced Scaffold NW_005871062.1 (1998310..2000815, complement)

NW_005871062.1Genomic Context describing neighboring genes Neighboring gene ATP synthase F(0) complex subunit C2, mitochondrial pseudogene Neighboring gene uncharacterized LOC106696392 Neighboring gene uncharacterized LOC102417347 Neighboring gene uncharacterized LOC111825110

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005871062 Unplaced Scaffold Reference Myoluc2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables E-box binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables N-box binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: transcription factor HES-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis lucifugus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Myoluc2.0

Genomic

  1. NW_005871062.1 Reference Myoluc2.0

    Range
    1998310..2000815 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006084756.3 → XP_006084818.1  LOW QUALITY PROTEIN: transcription factor HES-1

    UniProtKB/TrEMBL
    G1PBP0
    Related
    ENSMLUP00000007790.2, ENSMLUT00000008545.2
    Conserved Domains (2) summary
    cd00083
    Location:32 → 95
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam07527
    Location:110 → 148
    Hairy_orange; Hairy Orange
Nucleotide Protein
Heading Accession and Version

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