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ACACA acetyl-CoA carboxylase alpha [ Bubalus bubalis (water buffalo) ]

Gene ID: 102415834, updated on 10-Mar-2024

Summary

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Gene symbol
ACACA
Gene description
acetyl-CoA carboxylase alpha
See related
EnsemblRapid:ENSBALG00030040247
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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See ACACA in Genome Data Viewer
Location:
chromosome: 3
Exon count:
59
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 3 NC_059159.1 (49492847..49781587)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 3 NC_058345.1 (48917626..49206521)

Chromosome 3 - NC_059159.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123332705 Neighboring gene transcriptional adaptor 2A Neighboring gene chromosome 3 C17orf78 homolog Neighboring gene U6atac minor spliceosomal RNA Neighboring gene apoptosis antagonizing transcription factor Neighboring gene LIM homeobox 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables acetyl-CoA carboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetyl-CoA carboxylase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059159.1 Reference NDDB_SH_1 Primary Assembly

    Range
    49492847..49781587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025281124.3 → XP_025136909.1  acetyl-CoA carboxylase 1 isoform X2

    Related
    ENSBALP00030074049.1, ENSBALT00030111334.1
    Conserved Domains (5) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    COG0511
    Location:671 → 818
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region

  2. XM_044939574.2 → XP_044795509.1  acetyl-CoA carboxylase 1 isoform X2

    Related
    ENSBALP00030074039.1, ENSBALT00030111321.1
    Conserved Domains (5) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    COG0511
    Location:671 → 818
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region

  3. XM_044939575.2 → XP_044795510.1  acetyl-CoA carboxylase 1 isoform X2

    Conserved Domains (5) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    COG0511
    Location:671 → 818
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region

  4. XM_025281123.3 → XP_025136908.1  acetyl-CoA carboxylase 1 isoform X2

    Related
    ENSBALP00030074001.1, ENSBALT00030111272.1
    Conserved Domains (5) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    COG0511
    Location:671 → 818
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region

  5. XM_025281125.3 → XP_025136910.1  acetyl-CoA carboxylase 1 isoform X2

    Conserved Domains (5) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    COG0511
    Location:671 → 818
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region

  6. XM_025281122.3 → XP_025136907.2  acetyl-CoA carboxylase 1 isoform X1

    Related
    ENSBALP00030074032.1, ENSBALT00030111310.1
    Conserved Domains (4) summary
    cd06850
    Location:753 → 818
    biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    COG0511
    Location:671 → 818
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    cl40687
    Location:1646 → 2200
    Carboxyl_trans; Carboxyl transferase domain

  7. XM_025281126.3 → XP_025136911.2  acetyl-CoA carboxylase 1 isoform X3

    Conserved Domains (4) summary
    cd06850
    Location:753 → 818
    biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    COG0511
    Location:671 → 818
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    cl40687
    Location:1654 → 2131
    Carboxyl_trans; Carboxyl transferase domain
Nucleotide Protein
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